ReviewJournal of pharmacy & bioallied sciences2025
Systematic Review and Meta-Analysis to Explore the Relationship of Increased Homocysteine, Lipid Levels and Lipid Ratios In-Cad.
Review in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Coronary artery disease (CAD) is a leading cause of morbidity and mortality globally, with elevated homocysteine levels increasingly recognized as an independent risk factor. This meta-analysis aims to evaluate the relationship between homocysteine levels and CAD risk by pooling data from multiple studies. Materials and Methods: A comprehensive meta-analysis was conducted using data from 25 studies. Random-effects models were used to calculate pooled odds ratios (OR) and 95% confidence intervals (CI), accounting for heterogeneity among studies. Results: The pooled results showed a significant association between elevated homocysteine levels and increased risk of CAD, with a combined OR indicating a moderate but consistent effect size across studies. Conclusion: Elevated homocysteine levels are significantly associated with an increased risk of CAD. These findings support the incorporation of homocysteine measurement into cardiovascular risk assessment protocols.
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