ArticleJournal of pharmacy & bioallied sciences2025
Safety and Efficacy of Different Sedation Protocols in Managing Dental Anxiety in Adult Patients: A Randomized Controlled Trial.
Article in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Introduction: Dental anxiety is a significant barrier to effective dental treatment, often resulting in delayed care. Various sedation protocols are utilized to manage this anxiety, but comparative data on their safety and efficacy are limited. Methods: This randomized controlled trial compared the safety and efficacy of oral midazolam, nitrous oxide, and intravenous (IV) sedation in managing dental anxiety in adult patients. Key parameters included anxiety reduction using the Visual Analog Scale (VAS), time to onset of sedation, patient satisfaction, and adverse effects. Results: Patients receiving IV sedation showed the fastest onset and highest anxiety reduction, but oral midazolam exhibited fewer side effects. Patient satisfaction was highest with IV sedation. Conclusion: IV sedation was found to be the most effective in reducing anxiety, while oral midazolam offered better safety. Future studies should further explore patient-specific protocols.
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