ReviewJournal of pharmacy & bioallied sciences2025
Evaluating the Effectiveness of Platelet Rich Plasma Therapy in Enhancing Endometrial Receptivity for Women with Infertility: A Narrative Review.
Review in Journal of pharmacy & bioallied sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Platelet-Rich Plasma in Recurrent Pregnancy Loss: Toward a Precision Medicine Framework for Biologically Guided Patient Selection.Medical sciences (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infertility is a condition that affects a significant percentage of couples globally, affecting their social and psychological well-being. It disrupts many aspects of life, influencing individuals' social and psychological experiences. The primary causes of infertility are diverse and include endogenous factors, various psychological variables, congenital or acquired disorders in females, and genetic and hormonal issues in males. In females, implantation failure is a key obstacle to successful embryo implantation, with poor endometrial receptivity being a major contributing factor. Several methods have been explored to enhance endometrial thickness and improve implantation success rates. These include treatments such as granulocyte-colony stimulating factor, low-dose acetylsalicylic acid, vaginal sildenafil, and estrogens. Among these, platelet-rich plasma (PRP) has emerged as a promising approach. PRP, derived from the patient's own blood, is rich in growth factors such as platelet-derived growth factor (PDGF), transforming growth factor (TGF), epidermal growth factor (EGF), and vascular endothelial growth factor (VEGF). These factors are crucial in promoting cell replication and tissue regeneration. PRP therapy has shown significant potential in enhancing endometrial proliferation and improving pregnancy rates, particularly in patients with thin endometrium and those with a history of recurrent implantation failure. Numerous studies have reported that intrauterine PRP treatment leads to increased endometrial thickness and better clinical pregnancy outcomes. The PRP is obtained through a centrifugation process that separates platelet-rich plasma from red blood cells. This PRP is then injected into the endometrial cavity, typically midcycle, to boost endometrial receptivity. Systematic reviews have consistently highlighted the positive effects of PRP treatment on pregnancy outcomes in women with thin endometrium, offering hope to those facing challenges with implantation and fertility. PRP therapy represents a promising advancement in reproductive medicine, providing an effective option for improving endometrial receptivity and achieving successful pregnancies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.