Evidence map›Paper›PMID 40510622›Full record

ArticleJournal of experimental orthopaedics2025

Increased implant thickness in mechanically aligned off-the-shelf total knee replacement compared to bone resection.

Filippo Calanna, Riccardo Compagnoni, Luca Tanel, Alessandra Menon, Alessio Maione, Carlo Minoli, Paolo Ferrua, Pietro Simone Randelli

Abstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Filippo Calanna1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milan Italy.
Riccardo Compagnoni1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milan Italy.
Luca Tanel1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milan Italy.ORCID https://orcid.org/0009-0009-2536-359X
Alessandra Menon1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milan Italy.
Alessio Maione1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milan Italy.
Carlo MinoliU.O.C Week Surgery, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milan Italy.
Paolo Ferrua1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milan Italy.
Pietro Simone Randelli1° Clinica Ortopedica, ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO Milan Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Total knee arthroplasty (TKA) with mechanical alignment (MA) aims to align the leg neutrally, optimising stability and load distribution. To achieve this, bone cuts are performed, modifying the constitutional alignment of the knee and determining a mismatch between the implant thickness and the bone resection across the various compartments of the knee (bone-implant mismatch). This study aims to quantify the bone-implant mismatch in TKA with MA using an off-the-shelf implant and investigate how this ratio is influenced by the preoperative coronal knee alignment phenotype. Methods: Data from 100 patients who underwent primary off-the-shelf TKA with MA with a medial pivot design implant from January 2021 to September 2023 were analysed. Preoperative alignment phenotype was determined via long-leg weightbearing radiographs. During surgery, bone resections were measured with a caliper for each compartment. Bone-implant mismatch was determined for each compartment, analysing differences between medial and lateral compartments and the influence of preoperative alignment phenotype. Results: The overall implant thickness was 14.2% greater than the bone resection. In the patello-femoral compartment the implant thickness was 16.0% ± 19.0 less than the bone resection. Bone-implant mismatch was observed in the tibio-femoral joint across all the compartments with a significant difference between medial and lateral ( Conclusions: In mechanically aligned off-the-shelf TKA, implant thickness exceeds bone resection by an average of 14.2%, with a consistent bone-implant mismatch observed in all tibiofemoral compartments-significantly greater medially than laterally. Conversely, in the patellofemoral joint, bone resection surpasses implant thickness. Preoperative coronal alignment phenotype does not significantly influence this mismatch. These findings highlight a systematic discrepancy between bone resections and implant geometry, suggesting potential benefits from adjusted surgical techniques or implant design modifications to improve anatomical congruence and joint kinematics. Level of Evidence: Level III.

Indexed as

bone–implant mismatchkneemechanical alignmentoff‐the‐shelf knee prothesistotal knee arthroplasty

Identifiers

PMID40510622
PMCPMC12159454

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.