ReviewHealth science reports2025
Association Between Maternal Undernutrition and Pre-Labor Rupture of Membranes in Ethiopia: A Systematic Review and Meta-Analysis of Observational Studies.
Review in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: In Ethiopia, pre-labor rupture of membranes impacts maternal and perinatal health, while maternal undernutrition remains a major public health issue. The findings of previous studies have been inconsistent, and no nationwide pooled data exist. Therefore, this review aims to investigate the association between maternal undernutrition and pre-labor rupture of membranes in Ethiopia. Methods: Comprehensive and systematic searches were conducted across various databases, including PubMed, Google Scholar, Hinari, and ScienceDirect. The data were extracted using Microsoft Excel and analyzed with STATA version 17. The risk of bias and certainty of the evidence were evaluated. Heterogeneity was assessed using Results: A total of twelve observational studies, involving 4016 participants, were included in this systematic review and meta-analysis. Most studies showed a low risk of bias and a moderate level of certainty in the evidence. The pooled results indicated a significant association between maternal undernutrition and pre-labor rupture of membranes in Ethiopia (pooled OR = 3.24; 95% CI: 2.08-5.06), with substantial heterogeneity ( Conclusion: This meta-analysis shows a significant association between maternal undernutrition and an increased risk of pre-labor rupture of membranes in Ethiopia. Therefore, health institutions should assess the nutritional status of pregnant women during prenatal visits for counseling and supplementation programs. Policymakers need to develop public health policies to address maternal nutrition. We recommend further research that explore the role of specific nutrient deficiencies in pre-labor rupture of membranes. Review Registration ID: PROSPERO CRD42024579002.
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