Evidence map›Paper›PMID 40510521›Full record

ArticleHealth science reports2025

Multidrug-Resistant ESKAPEEc Pathogens From Bloodstream Infections in South Africa: A Cross-Sectional Study Assessing Resistance to WHO AWaRe Antibiotics.

Bakoena A Hetsa, Jonathan Asante, Daniel G Amoako, Akebe L K Abia, Joshua Mbanga, Sabiha Y Essack

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. High burden of blaBMC microbiology · 2026
    Article
  2. Review
  3. Virulome Landscape of Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bakoena A HetsaAntimicrobial Research Unit, College of Health Sciences University of KwaZulu-Natal Durban South Africa.
Jonathan AsanteAntimicrobial Research Unit, College of Health Sciences University of KwaZulu-Natal Durban South Africa.
Daniel G AmoakoAntimicrobial Research Unit, College of Health Sciences University of KwaZulu-Natal Durban South Africa.ORCID https://orcid.org/0000-0003-3551-3458
Akebe L K AbiaAntimicrobial Research Unit, College of Health Sciences University of KwaZulu-Natal Durban South Africa.
Joshua MbangaAntimicrobial Research Unit, College of Health Sciences University of KwaZulu-Natal Durban South Africa.
Sabiha Y EssackAntimicrobial Research Unit, College of Health Sciences University of KwaZulu-Natal Durban South Africa.ORCID https://orcid.org/0000-0003-3357-2761

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Multidrug-resistant (MDR) pathogens, particularly members of the ESKAPE group and Methods: Between November 2017 and December 2018, blood samples ( Results: Out of 195 presumptive isolates, 159 were confirmed as ESKAPEEc. The most frequently identified pathogens were Conclusion: The findings reveal a high burden of MDR ESKAPEEc in BSIs and widespread resistance to WHO Watch antibiotics. Targeted antimicrobial stewardship and the implementation of microbiology-guided therapy are urgently needed to optimize patient outcomes and curb the spread of resistance.

Indexed as

antimicrobial resistancebloodstream infectionsMAR indexmultidrug resistancepathogensWHO AWaRe

Identifiers

PMID40510521
PMCPMC12158662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.