Evidence map›Paper›PMID 40510436›Full record

ArticlePlastic and reconstructive surgery. Global open2025

Truth or Myth: Is Breast Implant Illness Really an Illness?

Rami Hanna, Udi Maor, Meir Retchkiman, Basel Abu-Ganem, Julie Vaynshtein, Eldad Silberstein

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rami HannaFrom the Faculty of Health Sciences, Joyce and Irving Goldman Medical School, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Udi MaorDepartment of Plastic and Reconstructive Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Meir RetchkimanDepartment of Plastic and Reconstructive Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Basel Abu-GanemDepartment of Plastic and Reconstructive Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Julie VaynshteinDepartment of General Surgery (B), Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Eldad SilbersteinDepartment of Plastic and Reconstructive Surgery, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Breast implant illness (BII) represents symptoms linked to silicone gel-filled breast implants. Research on BII remains limited, yielding contradictory conclusions. This study compared symptoms among healthy women with breast implants to those without breast implants. Methods: A single-blind questionnaire-based survey of asymptomatic female patients attending cancer screening was conducted at the Breast Health Center in Soroka Medical Center and at a breast surgeon's community clinic in Beer Sheva, Israel. The study included women with breast implants (implanted group) and those without implants or any other breast procedures (naive group). The questionnaire collected social, medical, and symptom data, stratified using the Index of Symptoms' Severity (ISS) scale. Results: Out of 181 women, 13 were excluded. The implanted group (n = 34) was compared with women without prior breast surgery, including implants (n = 134). Significant differences emerged in dry skin and sleeping problems, with higher rates in the naive group. However, overall symptom severity, measured by the ISS, showed no significant difference. Regression analysis indicated age and rheumatoid history correlated with the ISS, whereas breast implant augmentation was not a significant predictor. Conclusions: This study explored BII prevalence by comparing symptoms in women with breast implants to those without prior breast surgical interventions. Overall, symptom severity demonstrated no significant differences. Age and preexisting rheumatoid conditions may influence symptoms more than breast augmentation. The study's cross-sectional design, small sample size, and self-reported data could limit its findings. Further research is needed to understand BII's impact on well-being and safety.

Identifiers

PMID40510436
PMCPMC12160740

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.