Evidence map›Paper›PMID 40510295›Full record

ArticleCurrent research in toxicology2025

Thallium (III) disrupts the cell cycle and induces oxidative DNA damage in human lymphocytes

Alejandra López-Lanuza, Lucila Álvarez-Barrera, Hugo López-Muñoz, Rodrigo Aníbal Mateos-Nava, Juan José Rodríguez-Mercado

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Article in Current research in toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alejandra López-LanuzaUnidad de Investigación en Genética y Toxicología Ambiental. Unidad Multidisciplinaria, de Investigación Experimental (UMIE-Z), Facultad de Estudios Superiores Zaragoza (FES-Z), Campus II, UNAM, Ciudad de México 09230, Mexico.
Lucila Álvarez-BarreraUnidad de Investigación en Genética y Toxicología Ambiental. Unidad Multidisciplinaria, de Investigación Experimental (UMIE-Z), Facultad de Estudios Superiores Zaragoza (FES-Z), Campus II, UNAM, Ciudad de México 09230, Mexico.
Hugo López-MuñozLaboratorio Biología Molecular del Cáncer, UMIE-Z, Facultad de Estudios Superiores-Zaragoza, Campus II, UNAM, Ciudad de México 09230, Mexico.
Rodrigo Aníbal Mateos-NavaUnidad de Investigación en Genética y Toxicología Ambiental. Unidad Multidisciplinaria, de Investigación Experimental (UMIE-Z), Facultad de Estudios Superiores Zaragoza (FES-Z), Campus II, UNAM, Ciudad de México 09230, Mexico.
Juan José Rodríguez-MercadoUnidad de Investigación en Genética y Toxicología Ambiental. Unidad Multidisciplinaria, de Investigación Experimental (UMIE-Z), Facultad de Estudios Superiores Zaragoza (FES-Z), Campus II, UNAM, Ciudad de México 09230, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thallium (Tl) is considered hazardous to health because of its high toxicity and is an emerging contaminant with two oxidation states: Tl (I) and Tl (III). However, the toxicity of Tl and its compounds can be influenced by the oxidation state of the metal. Tl (III) is the least studied oxidation state of Tl, although it may affect cell proliferation and has genotoxic potential. Therefore, the aim of the present study was to analyze the effects Tl (III) chloride (TlCl

Indexed as

Cell proliferationDNA damageFormamidopyrimidine DNA-glycosylase (FPG)GenotoxicityNitrogen base oxidationTlCl3

Identifiers

PMID40510295
PMCPMC12159929

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.