ArticleJournal of dentistry (Shiraz, Iran)2025
The Effects of the Incorporation of Nano-Hydroxyapatite on Physico-Chemical Properties of Calcium-Enriched Mixed Cement.
Article in Journal of dentistry (Shiraz, Iran), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Calcium-enriched mixed (CEM) cement, though beneficial in endodontic applications, requires improvements in its physico-chemical properties to enhance clinical outcomes. Purpose: This study was conceptualized to investigate the impact of incorporating nano-hydroxyapatite (nHAP) on the physico-chemical properties of CEM cement. Materials and Method: In this experimental study, nHAP powder at 5 and 10 wt% ratio was thoroughly mixed with CEM cement powder. Then they were mixed with a ratio of 1 g of powder to 0.33g of liquid and placed in special molds for each test. CEM cement without nHAP was used as a control sample. Samples were assessed for setting time, compressive strength, solubility, and pH. Results: According to our results, the addition of 5% nHAP significantly increased the initial setting time (S1) and compressive strength after 24 hours, while the addition of 5% and 10% nHAP significantly enhanced the pH of the CEM cement. Conclusion: Incorporation of 5% nHAP to CEM cement, although delayed S1 of this cement, but increased the pH level of CEM cement, which in turn could potentially improve the antimicrobial properties of CEM cement. Furthermore, the addition of 5% nHAP to CEM cement notably improved the compressive strength in the short term, which can be beneficial in withstanding the chewing forces after applying the cement in the oral environment. It is recommended to select an appropriate concentration of nHAP to optimize the properties of CEM cement based on the findings of this study.
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