Evidence map›Paper›PMID 40510085›Full record

ArticleCureus2025

An Imitator Within: A Case of Appendiceal Neuroma Masquerading as Chronic Appendicitis.

Zhen Yun Siew, Ghee Khang Ong, Chia Ting Khoo, Siew Tung Wong, Kenny Voon

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhen Yun SiewSchool of Pharmacy, University of Nottingham Malaysia, Semenyih, MYS.
Ghee Khang OngSchool of Medicine, IMU University, Kuala Lumpur, MYS.
Chia Ting KhooSchool of Biosciences, University of Nottingham Malaysia, Semenyih, MYS.
Siew Tung WongDepartment of Pathology and Pharmacology, School of Medicine, IMU University, Kuala Lumpur, MYS.
Kenny VoonDivision of Biomedical Sciences, University of Nottingham Malaysia, Semenyih, MYS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of appendicitis, an inflammation of the appendix, has been rising significantly in many countries worldwide. Appendicitis may present in various forms, including acute or chronic inflammation, and can manifest as either uncomplicated or complicated conditions, etc. Among these conditions, chronic appendicitis is a rare type of appendiceal inflammation that is less common than acute appendicitis. In this case report, we describe a case of idiopathic appendiceal neuroma, which was initially misdiagnosed as acute gastroenteritis. Diagnosis was further supported by comprehensive laboratory testing, computed tomography and ultrasound imaging, as well as immunohistochemical staining. The patient made a full recovery following a laparoscopic appendectomy. This case highlights appendiceal neuroma as an elusive entity with atypical presentation of appendicitis and chronic histological features, emphasising the critical role of histopathology in establishing a definitive diagnosis.

Indexed as

appendicitischronicfibrous obliterationgastroenteritisneuroma

Identifiers

PMID40510085
PMCPMC12159277

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.