ArticleRSC advances2025
Combined antimicrobial and anti-inflammatory properties of electrospun PCL nanohybrids infused with metal-turmeric oleoresin and metalcurcuminoids.
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Defect and interface engineering of visible-light-active semiconductor nanomaterials for sustainable photocatalytic pathogen inactivation.Nanoscale advances · 2026Review
- Antimicrobial nanomaterials at the nanoscale: design principles, mechanisms, and global challenges.Nanoscale advances · 2026Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing risk of microbial infections and antimicrobial resistance requires the development of sustainable biomaterials with improved therapeutic properties for effective and environmentally friendly health and safety applications, leading to the exploration of advanced multifunctional nanomaterials. This study introduces a novel electrospun polymeric membrane that integrates a trimetallic nanohybrid composed of silver (Ag), copper (Cu), and nickel (Ni) with curcuminoids derived from turmeric oleoresin. This combination is incorporated into a biodegradable polycaprolactone (PCL) electrospun mat. The synthesis and characterization of the nanohybrids were performed using Fourier-transform infrared spectroscopy (FTIR), Raman spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), and UV diffuse reflectance spectrometry. The electrospun membranes incorporated with a trimetallic and curcuminoids nanohybrid demonstrated a synergistic antimicrobial effect, as evidenced by inhibition zones measuring between 29.67 ± 0.24 and 33.17 ± 0.24 mm against a wide range of bacterial and fungal strains. The primary antimicrobial mechanism is attributed to radical scavenging activity (RSA), which reached a maximum value of 76.14 ± 0.99% in the trimetallic and curcuminoids nanohybrid incorporated PCL mat. Furthermore, the curcuminoids displayed significant anti-inflammatory effects, achieving a maximum reduction of 72.81 ± 0.33% at a concentration of 5000 ppm. The electrospun membranes effectively reduce microbial growth, are biodegradable, non-toxic, pose minimal hazards, and are environmentally friendly, aligning with sustainable technologies for biomedical applications. These membranes function as physical and biological barriers, offering an eco-conscious, cost-effective alternative to conventional antimicrobial strategies. This research highlights the potential of trimetallic-curcuminoid nanohybrid electrospun membranes as sustainable biomaterials for advanced antimicrobial treatments, contributing to safer and more effective biomedical applications while ensuring biocompatibility and environmental safety. It exemplifies how innovative solutions can tackle health and sustainability challenges.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.