Evidence map›Paper›PMID 40510028›Full record

ArticleCancer drug resistance (Alhambra, Calif.)2025

ZEB2 upregulation modulates the polarization of TAMs toward the immunosuppressive state in EGFR-TKI-resistant NSCLC.

Yunhuan Liu, Yong Yu, Congli Hu, Minlin Jiang, Chao Zhao, Xuefei Li, Lei Cheng, Caicun Zhou

Abstract read
In one paragraph

Article in Cancer drug resistance (Alhambra, Calif.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yunhuan LiuDepartment of oncology, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai 200433, China.
Yong YuDepartment of Radiology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Yancheng 224002, Jiangsu, China.
Congli HuDepartment of oncology, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai 200433, China.
Minlin JiangDepartment of oncology, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai 200433, China.
Chao ZhaoDepartment of oncology, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai 200433, China.
Xuefei LiDepartment of oncology, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai 200433, China.
Lei ChengDepartment of oncology, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai 200433, China.
Caicun ZhouDepartment of oncology, Shanghai East Hospital Affiliated to Tongji University, No.1800 Yuntai Road, Pudong New District, Shanghai 200120, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EGFR-TKI resistanceimmunotherapy resistancePI3K-Akt pathwaytumor-associated macrophages (TAMs)tumor microenvironment (TME)ZEB2

Identifiers

PMID40510028
PMCPMC12159605

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.