ArticleInternational endodontic journal2025
2D versus 3D radiographic assessment of asymptomatic persistent endodontic lesions.
Article in International endodontic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The trial behind it
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Who cites it
4 citing papers in PubMed.
- Reference Standards in Artificial Intelligence Detection of Apical Periodontitis: A Narrative Review of What Reported Accuracy Measures.Diagnostics (Basel, Switzerland) · 2026Review
- Clinical Readiness of Artificial Intelligence Models for MB2 Canal Detection in Maxillary Molars: A Scoping Review.International dental journal · 2026Article
- Apical Gap, Adaptation, and Trueness of Direct and Indirect Customized Post-and-Core Restorations Fabricated by the Casting, Milling, and Selective Laser Melting Techniques.International journal of dentistry · 2026Article
- 2D versus 3D radiographic assessment of asymptomatic persistent endodontic lesions.International endodontic journal · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
aimThis prospective cohort study aimed to study lesion size, proximity to anatomical structures and detection of missed canals using 2D digital periapical (PA) radiographs and 3D cone beam computed tomography (CBCT) radiographic imaging, amongst a cohort of asymptomatic persistent endodontic lesions (APEL), and to develop a radiographic protocol for these asymptomatic lesions. METHODOLOGY: APEL persisting ≥4 years after endodontic treatment were recruited with informed consent. PA radiographs taken at different angles (KaVo Kerr, Brea, CA) and a limited field-of-view CBCT scan (KaVo Kerr, Brea, CA) of 0.125mm
resultsEighty-two APEL (15 incisors, 25 premolars, 42 molars; 59.8% treated 4-10 years prior) in 77 patients (34 male, 43 female, median age 51-60) were examined. Root filling quality was acceptable with 14/82 (17.0%) lacking density and homogeneity. Weighted kappa on lesion size (0.5-1.9, 2-4.9 and 5-9.9 mm) between PA radiographs and CBCT was 0.466 - in 24 APEL, lesion size was >2 mm larger on CBCT whilst in 4 APEL, lesions were >2 mm smaller on CBCT. On proximity to maxillary sinus and neurovascular structures ('yes', 'no', 'unable to tell'), kappa was 0.237, with 9 APEL scored 'unable to tell' on PA radiographs and 0 uncertainty on CBCT. Agreement between PA radiographs and CBCT on missed canals ('not likely', 'somewhat likely', 'very likely', 'unable to tell') was 0.349, with 13 teeth scored 'somewhat likely' and 'very likely' on CBCT and only 6 teeth similarly scored on PA.
conclusionOverall, CBCT provided a more comprehensive examination of teeth with APEL than PA radiographs. Larger lesion sizes were generally observed, especially in posterior teeth. Sinus involvement was more readily identified, and the assessment of the presence of missed canals could be performed with more certainty. Where lesion monitoring is chosen, CBCT imaging should be considered for a more thorough assessment of posterior teeth, and where there is uncertainty in PA radiograph interpretation of anterior teeth.
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