Evidence map›Paper›PMID 40509587›Full record

ArticleEnvironmental microbiology reports2025

Enzymatic Strategies for Biocontrolling Phytopathogenic Fungi Using Trichoderma Koningiopsis LBM116.

Natalia Soledad Amerio, Marcela Paola Barengo, Gustavo Angel Bich, Pedro Dario Zapata, Laura Lidia Villalba, María Lorena Castrillo

Abstract read
In one paragraph

Article in Environmental microbiology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalia Soledad AmerioUniversidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y, Naturales. Instituto de Biotecnología Misiones "Dra. María Ebe Reca"-InBioMis. Laboratorio de Biotecnología Molecular, Posadas, Argentina.ORCID https://orcid.org/0000-0003-4342-9977
Marcela Paola BarengoUniversidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y, Naturales. Instituto de Biotecnología Misiones "Dra. María Ebe Reca"-InBioMis. Laboratorio de Biotecnología Molecular, Posadas, Argentina.ORCID https://orcid.org/0000-0003-1814-9690
Gustavo Angel BichUniversidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y, Naturales. Instituto de Biotecnología Misiones "Dra. María Ebe Reca"-InBioMis. Laboratorio de Biotecnología Molecular, Posadas, Argentina.
Pedro Dario ZapataUniversidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y, Naturales. Instituto de Biotecnología Misiones "Dra. María Ebe Reca"-InBioMis. Laboratorio de Biotecnología Molecular, Posadas, Argentina.ORCID https://orcid.org/0000-0001-6476-8324
Laura Lidia VillalbaUniversidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y, Naturales. Instituto de Biotecnología Misiones "Dra. María Ebe Reca"-InBioMis. Laboratorio de Biotecnología Molecular, Posadas, Argentina.ORCID https://orcid.org/0009-0000-3385-6743
María Lorena CastrilloUniversidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y, Naturales. Instituto de Biotecnología Misiones "Dra. María Ebe Reca"-InBioMis. Laboratorio de Biotecnología Molecular, Posadas, Argentina.ORCID https://orcid.org/0000-0002-4999-1672

Funding

Consejo Nacional de Investigaciones Científicas y TécnicasProyectos de Investigación Científica y Tecnológica 11220210100916C0Proyectos de Investigación Científica y Tecnológica 2016-3349Proyectos de Investigación Científica y Tecnológica 2021 - GRF TI - 0528
6 · The paper itself

Abstract

The growing demand for sustainable alternatives to chemical fungicides has driven the development of microbial-based biocontrol strategies. In this study, the native strain Trichoderma koningiopsis LBM116 (Misiones, Argentina) was optimised for the production of mycolytic enzymes (chitinases, β-1,3-glucanases, and proteases) using factorial and response surface experimental designs. Enzyme secretion was increased by more than 250% compared to initial conditions by selecting specific carbon and nitrogen sources and adjusting inoculum and pH parameters. The optimised enzyme formulation improved lettuce seed germination to 86.66% in the presence of the phytopathogen Fusarium sp., under controlled conditions. In seedling trials, it also reduced disease severity and improved growth parameters. These results confirm the dual effect of the enzyme formulation, acting as a biocontrol agent and plant growth promoter. This work highlights the potential of enzyme formulations derived from T. koningiopsis LBM116 as an effective, low-cost, and sustainable alternative for managing phytopathogens in agriculture.

Indexed as

Biological Control AgentsFungal ProteinsFusariumPlant DiseasesTrichodermaChitinasesGerminationGlucan 1,3-beta-GlucosidaseLactucaPeptide HydrolasesBiological Control AgentsChitinasesFungal ProteinsGlucan 1,3-beta-GlucosidasePeptide Hydrolasesbiological controlchitinasesenzymatic formulationglucanasesproteasessustainable agriculture

Identifiers

PMID40509587
PMCPMC12162947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.