ArticleFoods (Basel, Switzerland)2025
Dual-Mode Microfluidic Workstation for Rapid Detection of Multiple Mycotoxins on Chip.
Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Origins of Atlantic Salmon (Biosensors · 2026Article
- Remote-Controlled Microfluidic Platform for Real-Time Detection of Multiple Mycotoxins on Chip.Foods (Basel, Switzerland) · 2026Article
- Review
- Development of a Novel Aptamer-Antibody Sandwich Chemiluminescent Biosensor and Its Application in the Detection of Aflatoxin BBiosensors · 2025Article
- AI-Powered Innovations in Food Safety from Farm to Fork.Foods (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The assurance of food safety requires sensitive monitoring of multiple mycotoxins due to their severe impacts on the food industry and high health risks posed to consumers. Herein, we proposed a chemiluminescent/colorimetric dual-signal readout microfluidic method, incorporating a streptavidin-biotin-alkaline phosphatase (SA-Biotin-ALP) signal amplification system for the highly sensitive detection of Deoxynivalenol (DON), Ochratoxin A (OTA), and Aflatoxin B1 (AFB1). The indirect competitive enzyme-linked immunoassay (ic-ELISA) was integrated into microfluidic chip, resulting in sensitive detection ranges of DON in the range of 4-128 ng/mL, 2-64 ng/mL for OTA, and 0.2-6.4 ng/mL for AFB1, with the limit of detection (LOD) being 2.636 ng/mL, 1.492 ng/mL, and 0.131 ng/mL, respectively. Recovery rates in beer samples ranged from 91.93% to 109.31%. Furthermore, a dual-mode microfluidic workstation (DMMW) was developed to facilitate rapid, automated detection for these mycotoxins, simplifying the detection procedure, enhancing the detection efficiency, and reducing the requirement for specialized personnel, thus confirming significant potential for the rapid detection of mycotoxins in complex matrices such as beer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.