Evidence map›Paper›PMID 40509445›Full record

ReviewFoods (Basel, Switzerland)2025

Plant-Based Diet for Glycemic Control, Insulin Sensitivity, and Lipid Profile in Type 2 Diabetes: A Systematic Review.

Siwatt Thaiudom, Kakanang Posridee, Sunthara Liangchawengwong, Chantira Chiaranai, Saranya Chularee, Aoitip Samanros, Anant Oonsivilai, Naruemol Singha-Dong, Ratchadaporn Oonsivilai

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siwatt ThaiudomHealth and Wellness Research Unit, School of Food Technology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0001-9546-856X
Kakanang PosrideeHealth and Wellness Research Unit, School of Food Technology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0009-0005-7024-5841
Sunthara LiangchawengwongInstitute of Nursing, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Chantira ChiaranaiInstitute of Nursing, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0002-7566-6160
Saranya ChulareeInstitute of Nursing, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Aoitip SamanrosSchool of Nutrition and Dietitian, Institute of Public Health, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Anant OonsivilaiSchool of Electrical Engineering, Institute of Engineering, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0002-6473-1852
Naruemol Singha-DongInstitute of Nursing, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0003-1486-5390
Ratchadaporn OonsivilaiHealth and Wellness Research Unit, School of Food Technology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0002-5266-8411

Funding

Institute of Research and Development, Suranaree University of Technology HS8-807-66-12-05
6 · The paper itself

Abstract

BACKGROUND/

objectiveType 2 diabetes mellitus (T2D) is a chronic metabolic disorder characterized by hyperglycemia. Plant-based interventions have gained attention as potential complementary treatments alongside conventional therapies. This systematic review evaluates the efficacy of plant-based interventions in improving glycemic control, insulin sensitivity, lipid profiles, and other outcomes such as GLUT-4, Tumor Necrosis Facto-alpha, dietary inflammation index, plasma lipopolysaccharide, total antioxidant capacity, and malondialdehyde in individuals with T2D.

methodsWe conducted a systematic search of PubMed, Scopus, and ScienceDirect databases to identify randomized controlled trials (RCTs) and observational studies. RCTs were used as an additional screening criterion. The review included studies on the effects of plant-based interventions, encompassing fruits, vegetables, herbs, spices, and their extracts. We analyzed data on glycemic control, insulin sensitivity, lipid profiles, and other metabolic markers.

resultsTwenty-six studies were included in our analysis. Various interventions showed potential benefits, with improved glycemic control, insulin sensitivity, and lipid profiles. Specific interventions such as

conclusionAlthough some plant-based interventions appear promising in managing T2D, the evidence remains inconclusive due to variability in study quality and methodology. Further high-quality RCTs are necessary to confirm these findings and to establish the optimal dosage, duration, and combinations of interventions for effective T2D management. Despite inconclusive results, few plant-based diets have promising outcomes. Healthcare providers, especially nurse case managers, can incorporate the findings of this study into their practice protocol to support self-management for individuals with TD2.

Indexed as

functional foodglycemic controlinsulin sensitivitylipid profileplant-based interventionsystematic reviewtype 2 diabetes mellitus (T2D)

Identifiers

PMID40509445
PMCPMC12154518

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.