ArticleMolecules (Basel, Switzerland)2025
Fabrication of Gliadin-Carboxymethyl Chitosan Composite Nanoparticles to Improve the Stability and Antioxidant Activity of Curcumin.
Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Protein-polysaccharide conjugation in food systems: Design principles, material and processing constraints, and functional outcomes.Food chemistry: X · 2026Review
- A Hybrid Nanosystem for Prostate Cancer Therapy: Codelivery of Enzalutamide and Curcumin via Selenium-Embedded Mesoporous Silica and Chitosan Nanoparticles.ChemistryOpen · 2026Article
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Authors and funding
10 authors.
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Abstract
The antisolvent precipitation method was employed to synthesize curcumin-loaded gliadin-carboxymethyl chitosan (CMCS) composite nanoparticles (GCC NPs). When the gliadin/CMCS weight ratio was 2:1, the GCC NPs with an ideal negative charge (-27.57 ± 1.07 mV) and the minimum particle size (184.13 ± 5.49 nm) were obtained. With the addition of CMCS, the encapsulation efficiency (EE) of Cur was markedly improved from 77.46 ± 1.54% to 93.88 ± 1.31%. Under various pH values and salt concentrations, the GCC NPs displayed excellent colloidal stability. Specifically, after encapsulation within the GCC NPs, the antioxidant activity of Cur was markedly improved. In ABTS and DPPH assays, the SC
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