Evidence map›Paper›PMID 40509272›Full record

ArticleMolecules (Basel, Switzerland)2025

Rose Bengal Conjugated to Lectins for Targeted Antibacterial Photodynamic Treatment.

Melad Atrash, Iryna Hovor, Marina Nisnevitch, Faina Nakonechny

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Melad AtrashDepartment of Chemical Engineering, Ariel University, Kiryat-ha-Mada, Ariel 40700, Israel.
Iryna HovorDepartment of Chemical Engineering, Ariel University, Kiryat-ha-Mada, Ariel 40700, Israel.
Marina NisnevitchDepartment of Chemical Engineering, Ariel University, Kiryat-ha-Mada, Ariel 40700, Israel.ORCID 0000-0001-8493-713X
Faina NakonechnyDepartment of Chemical Engineering, Ariel University, Kiryat-ha-Mada, Ariel 40700, Israel.ORCID 0000-0002-8973-1322

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to rising antibiotic resistance, it is necessary to develop alternative ways to combat pathogenic bacteria. One alternative is photodynamic antibacterial chemotherapy (PACT). This work presents the conjugation of the photosensitizer Rose Bengal (RB) to lectins to improve its efficacy against Gram-positive and Gram-negative bacteria. Two lectins, concanavalin A (ConA) and wheat germ agglutinin (WGA), were covalently linked to RB. Spectroscopic and chromatographic data confirmed successful conjugation. Microscopic examination demonstrated that both lectins agglutinate cells of Gram-positive

Indexed as

Anti-Bacterial AgentsLectinsPhotochemotherapyPhotosensitizing AgentsRose BengalConcanavalin AGram-Negative BacteriaMicrobial Sensitivity TestsStaphylococcus aureusWheat Germ AgglutininsAnti-Bacterial AgentsConcanavalin ALectinsPhotosensitizing AgentsRose BengalWheat Germ Agglutininsconcanavalin Aconjugationlectinsphotodynamic antibacterial activityphotosensitizersRose Bengal

Identifiers

PMID40509272
PMCPMC12156063

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.