Evidence map›Paper›PMID 40509269›Full record

ArticleMolecules (Basel, Switzerland)2025

Identification and Adulteration Evaluation of Rubiae Radix Et Rhizoma and Its Common Adulterants Based on LC-MS and Chemometrics.

Lihui Zhang, Ting Han, Xianrui Wang, Yu Zhang, Jiating Zhang, Wenguang Jing, Minghua Li, Xianlong Cheng, Feng Wei

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lihui ZhangInstitute for Control of Traditional Chinese Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing 102629, China.
Ting HanInstitute for Control of Traditional Chinese Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing 102629, China.
Xianrui WangInstitute for Control of Traditional Chinese Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing 102629, China.
Yu ZhangInstitute for Control of Traditional Chinese Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing 102629, China.
Jiating ZhangInstitute for Control of Traditional Chinese Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing 102629, China.
Wenguang JingInstitute for Control of Traditional Chinese Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing 102629, China.ORCID 0009-0001-5122-523X
Minghua LiInstitute for Control of Traditional Chinese Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing 102629, China.
Xianlong ChengInstitute for Control of Traditional Chinese Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing 102629, China.
Feng WeiInstitute for Control of Traditional Chinese Medicine and Ethnic Medicine, National Institutes for Food and Drug Control, Beijing 102629, China.ORCID 0000-0002-7598-0723

Funding

National Key R&D Program of China 2023YFC3504105
6 · The paper itself

Abstract

background

methodsAfter LC-MS analysis and data conversion, the ion intersections were taken from different batches of RSP, RMP, and RRR. Then, the proprietary ions of three herbs were obtained by taking the de-intersection. Finally, the top-

resultsThe identification evaluation of RRR can be realized based on the "ion identity", even if 3% RSP (or RMP) in RRR samples can still be recognized. Combined with chemometric analysis, three market samples were identified as adulterants, proving that identification evaluation based on "ion identity" is reasonable.

conclusionsThe "ion identity" based on LC-MS, which helps in realizing RRR identification evaluation. It has important reference significance for RRR analysis.

Indexed as

ChemometricsDrug ContaminationDrugs, Chinese HerbalRhizomeChromatography, LiquidLiquid Chromatography-Mass SpectrometryMass SpectrometryTandem Mass SpectrometryDrugs, Chinese Herbalchemometricsidentification evaluationLC-MSRubiae radix et rhizomaRubia magna P. G. XiaoRubia schumanniana E. Pritz.

Identifiers

PMID40509269
PMCPMC12156058

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.