Evidence map›Paper›PMID 40509036›Full record

ReviewAnimals : an open access journal from MDPI2025

Genetically Modified Animal-Derived Products: From Regulations to Applications.

Carlos Fajardo, Marta Macedo, Tonka Buha, Marcos De Donato, Benjamin Costas, Juan Miguel Mancera

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Pig Genome Editing for Agriculture: Achievements and Challenges.International journal of molecular sciences · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carlos FajardoDepartment of Biology, Faculty of Marine and Environmental Sciences, Instituto Universitario de Investigación Marina (INMAR), Campus de Excelencia Internacional del Mar (CEI·MAR), University of Cadiz (UCA), 11510 Puerto Real, Spain.ORCID 0000-0001-9403-2211
Marta MacedoInterdisciplinary Centre of Marine and Environmental Research, University of Porto (CIIMAR), 4450-208 Matosinhos, Portugal.ORCID 0009-0003-9470-0509
Tonka BuhaInterdisciplinary Centre of Marine and Environmental Research, University of Porto (CIIMAR), 4450-208 Matosinhos, Portugal.ORCID 0000-0002-0305-8174
Marcos De DonatoCenter for Aquaculture Technologies (CAT), San Diego, CA 92121, USA.ORCID 0000-0001-8860-6020
Benjamin CostasInterdisciplinary Centre of Marine and Environmental Research, University of Porto (CIIMAR), 4450-208 Matosinhos, Portugal.ORCID 0000-0003-3758-0849
Juan Miguel ManceraDepartment of Biology, Faculty of Marine and Environmental Sciences, Instituto Universitario de Investigación Marina (INMAR), Campus de Excelencia Internacional del Mar (CEI·MAR), University of Cadiz (UCA), 11510 Puerto Real, Spain.ORCID 0000-0003-0751-5966

Funding

Ministry of Universities of Spain 2021-067/PN/MS-RECUAL/CDUniversity of Cadiz UCA/REC64VIT/2024
6 · The paper itself

Abstract

Biotechnological advances applied to the generation of genetically modified (GM) animals have shown the potential to develop innovative solutions for different challenges in key areas such as agriculture and human medicine. Despite its enormous potential, the deployment of genetic modification in animals, and its subsequent commercialization, does not meet the same public acceptance as GM plant-derived products, which are currently widely adopted around the world. In this review, we highlight the main examples of GM and gene-edited animal-derived products already approved by the FDA and discuss the regulatory context inherent to such processes, including the risk-based assessment analysis based on a case-by-case evaluation. Moreover, cases of GM animals already approved by other jurisdictions around the world are also discussed.

Indexed as

CRISPRFDAgene-editinggenetic engineeringGMOintentional genomic alterations

Identifiers

PMID40509036
PMCPMC12153536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.