Evidence map›Paper›PMID 40508226›Full record

ArticleInternational journal of molecular sciences2025

Anti-Inflammatory Potential of Essential Oil from the Heart-Wood of the Folk Medicinal Tree

May-Lan Liu, Pang-Yen Liu, Louis Kuoping Chao, Tzu-Jung Yang, Lan-Hui Li, Yih-Ming Weng, Sarana Rose Sommano, Yuwalee Unpaprom, Rameshprabu Ramaraj, Chen-Lung Ho and 1 more

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

May-Lan LiuDepartment of Food Science, National Chiayi University, Chiayi 600355, Taiwan.
Pang-Yen LiuDivision of Cardiology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.
Louis Kuoping ChaoDepartment of Cosmeceutics, China Medical University, Taichung 406040, Taiwan.ORCID 0000-0003-1112-3850
Tzu-Jung YangDivision of Wood Cellulose, Taiwan Forestry Research Institute, Taipei 10066, Taiwan.
Lan-Hui LiDepartment of Laboratory Medicine, Linsen Chinese Medicine and Kunming Branch, Taipei City Hospital, Taipei 108203, Taiwan.
Yih-Ming WengDepartment of Food Science, National Chiayi University, Chiayi 600355, Taiwan.
Sarana Rose SommanoPlant Bioactive Compound Laboratory (BAC), Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-7356-2598
Yuwalee UnpapromSustainable Resources and Sustainable Engineering Research Lab, Maejo University, Chiang Mai 50290, Thailand.
Rameshprabu RamarajSustainable Resources and Sustainable Engineering Research Lab, Maejo University, Chiang Mai 50290, Thailand.ORCID 0000-0002-4141-9313
Chen-Lung HoDivision of Wood Cellulose, Taiwan Forestry Research Institute, Taipei 10066, Taiwan.ORCID 0000-0002-0354-034X
Kuo-Feng HuaDepartment of Biotechnology and Animal Science, National Ilan University, Ilan 260007, Taiwan.

Funding

National Science and Technology Council, Taiwan MOST 111-2628-B-197-001-MY3; NSTC 113-2313-B-197-002
6 · The paper itself

Abstract

Inflammation is a vital physiological response that plays a crucial role in regulating host defense against pathogens while maintaining tissue homeostasis. Inflammasomes, a family of protein complexes, are responsible for controlling the expression of pro-inflammatory cytokines IL-1β and IL-18, and they play significant roles in inflammatory responses. However, dysregulated inflammation can become a risk factor for the pathogenesis of various diseases. The discovery of anti-inflammatory substances derived from natural products represents an important strategy for new drug development. In this study, we found that the essential oil derived from the heartwood of

Indexed as

Anti-Inflammatory AgentsCinnamomumInflammasomesOils, VolatileAnimalsDrug Evaluation, PreclinicalHumansMiceMitochondriaNLR Family, Pyrin Domain-Containing 3 ProteinPlants, MedicinalTreesWoodAnti-Inflammatory AgentsInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanOils, Volatileanti-inflammatory agentCinnamomum kanehirai Hayatacytokinesessential oilsmacrophagesNLRP3 inflammasome

Identifiers

PMID40508226
PMCPMC12156951

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.