Evidence map›Paper›PMID 40508200›Full record

ReviewInternational journal of molecular sciences2025

From Chromosomal Aberrations to Transcriptome Analysis: Four Decades of Research in Bivalve Genotoxicity.

Zenaba Khatir, Alexandra Leitão

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zenaba KhatirEnvironmental Science Center, Qatar University, Doha 2713, Qatar.ORCID 0000-0002-1178-802X
Alexandra LeitãoEnvironmental Science Center, Qatar University, Doha 2713, Qatar.ORCID 0000-0001-8903-3797

Funding

Qatar Research Development and Innovation Council (QRDI) ARG01-0528-230371
6 · The paper itself

Abstract

Over the past four decades, bivalves have become sentinel organisms in genotoxicity research due to their ecological relevance and sensitivity to environmental contaminants. This integrative review critically examines the evolution of genotoxicity in bivalves, from early cytogenetic assays to advanced transcriptomic approaches. It highlights key methodological developments, geographical research trends, and the recent integration of multi-endpoint analyses for a more robust, consistent environmental risk assessment. By synthesizing data from four decades of research, we provide a comprehensive overview of current knowledge while also critically identifying persistent challenges and suggesting directions for future research to allow better evaluation and mitigation of the genetic impacts of marine pollution.

Indexed as

BivalviaChromosome AberrationsGene Expression ProfilingTranscriptomeAnimalsMutagenicity TestsMutagensMutagensbivalveschemical stressorcytogeneticsDNAgenegenotoxicitymolecular responsestranscriptomics

Identifiers

PMID40508200
PMCPMC12156399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.