Evidence map›Paper›PMID 40508195›Full record

ArticleInternational journal of molecular sciences2025

Suk-SaiYasna Remedy, a Traditional Thai Medicine, Mitigates Stress-Induced Cognitive Impairment via Keap1-Nrf2 Pathway.

Wuttipong Masraksa, Supawadee Daodee, Orawan Monthakantirat, Chantana Boonyarat, Charinya Khamphukdee, Pakakrong Kwankhao, Abdulwaris Mading, Poowanarth Muenhong, Juthamart Maneenet, Suresh Awale and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wuttipong MasraksaGraduate School of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0009-0008-0458-2091
Supawadee DaodeeDivision of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-2051-9953
Orawan MonthakantiratDivision of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-7331-8373
Chantana BoonyaratDivision of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-4065-6090
Charinya KhamphukdeeDivision of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-9927-0670
Pakakrong KwankhaoCenter of Evidence-Based for Traditional and Herbal Medicine, Chao Phya Abhaibhubejhr Hospital, Prachinburi 25000, Thailand.ORCID 0000-0001-6829-4349
Abdulwaris MadingGraduate School of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-3351-5441
Poowanarth MuenhongDivision of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Juthamart ManeenetNatural Drug Discovery Laboratory, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.ORCID 0000-0002-9926-7092
Suresh AwaleNatural Drug Discovery Laboratory, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.ORCID 0000-0002-5299-193X
Kinzo MatsumotoGraduate School of Pharmaceutical Sciences, Daiichi University of Pharmacy, Fukuoka 815-8511, Japan.
Yaowared ChulikhitDivision of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0001-7317-8721

Funding

Faculty of Pharmaceutical Sciences, Khon Kaen University ID: 66-1(7)/2566Graduate school, Khon Kaen University Project No. 641H222National Science, Research, and Innovation Fund FF67-200703
6 · The paper itself

Abstract

Suk-SaiYasna (SSY) is a well-documented traditional Thai herbal formula in the Royal Scripture of King Narai's Traditional Medicine. SSY contains

Indexed as

Cognitive DysfunctionKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2Plant ExtractsSignal TransductionStress, PsychologicalAnimalsAntioxidantsDisease Models, AnimalMaleMedicine, Thai TraditionalMiceNeuroprotective AgentsOxidative StressThailandAntioxidantsKeap1 protein, mouseKelch-Like ECH-Associated Protein 1Neuroprotective AgentsNfe2l2 protein, mouseNF-E2-Related Factor 2Plant ExtractscannabinoidCannabis sativachronic stresscognitive impairmentneuroprotectionNrf2/Keap1Suk-SaiYasna

Identifiers

PMID40508195
PMCPMC12154420

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.