Evidence map›Paper›PMID 40508194›Full record

ArticleInternational journal of molecular sciences2025

The Potential Role of Gonadotropic Hormones and Their Receptors in Sex Differentiation of Nile Tilapia,

He Gao, Hongwei Yan, Tomomitsu Arai, Chak Aranyakanont, Shuang Li, Shigeho Ijiri

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

He GaoDivision of Marine Life Sciences, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Hokkaido, Japan.ORCID 0009-0005-6950-6936
Hongwei YanDivision of Marine Life Sciences, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Hokkaido, Japan.
Tomomitsu AraiDivision of Marine Life Sciences, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Hokkaido, Japan.
Chak AranyakanontDivision of Marine Life Sciences, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Hokkaido, Japan.
Shuang LiDivision of Marine Life Sciences, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Hokkaido, Japan.
Shigeho IjiriDivision of Marine Life Sciences, Graduate School of Fisheries Sciences, Hokkaido University, Hakodate 041-8611, Hokkaido, Japan.

Funding

Japan Society for the Promotion of Science 23K2369603
6 · The paper itself

Abstract

Nile tilapia, as an ideal model for studying sex differentiation, is a popular farmed fish worldwide with a stable XX/XY sex-determination system. In tilapia, ovarian differentiation is triggered by estradiol-17β (E2) production in undifferentiated gonads. In a previous study, we suggested that follicle-stimulating hormone (FSH) signaling might be involved in ovarian differentiation in Nile tilapia. In this study, we further investigated the role of FSH signaling in ovarian differentiation via aromatase expression, which converts testosterone to E2. Masculinization of XX fry by aromatase inhibitor or 17α-methyltestosterone leads to suppression of

Indexed as

CichlidsFollicle Stimulating HormoneReceptors, FSHSex DifferentiationAnimalsAromataseEstradiolFemaleFish ProteinsHEK293 CellsHumansMaleOvarySignal TransductionAromataseEstradiolFish ProteinsFollicle Stimulating HormoneReceptors, FSHcyp19a1aFSH signalingNile tilapiasex differentiation

Identifiers

PMID40508194
PMCPMC12156293

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.