Evidence map›Paper›PMID 40508162›Full record

ArticleInternational journal of molecular sciences2025

Vat-Mediated Mucus Penetration Enables Genotoxic Activity of

Héloïse Chat, Léa Girondier, Guillaume Dalmasso, Caroline Vachias, Laurent Guillouard, Virginie Bonnin, Devon Kavanaugh, Aurélien Birer, Mathilde Bonnet, Nicolas Barnich and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Héloïse ChatMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.ORCID 0009-0001-5083-9870
Léa GirondierMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.ORCID 0009-0003-0451-5888
Guillaume DalmassoMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.ORCID 0000-0002-3433-870X
Caroline VachiasInstitut Génétique Reproduction & Développement (iGReD), University Clermont Auvergne, UMR CNRS 6293-Inserm U1103, 63001 Clermont-Ferrand, France.
Laurent GuillouardMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.
Virginie BonninMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.
Devon KavanaughMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.
Aurélien BirerMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.ORCID 0000-0001-7466-5783
Mathilde BonnetMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.ORCID 0000-0003-3629-7267
Nicolas BarnichMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.ORCID 0000-0001-9465-7844
Richard BonnetMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.
Julien DelmasMicrobes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Inserm U1071, INRAE USC 1382, University Clermont Auvergne, 63001 Clermont-Ferrand, France.ORCID 0000-0002-9579-0660

Funding

Inserm National Program "Microbiote" Inserm
6 · The paper itself

Abstract

Colibactin toxin-producing

Indexed as

Bacterial ToxinsEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsIntestinal MucosaMucusPeptidesPolyketidesAnimalsDNA DamageHT29 CellsHumansMiceMucin-2Bacterial ToxinscolibactinEscherichia coli ProteinsMucin-2PeptidesPolyketidescolibactincolorectal cancerEscherichia colimucinpks

Identifiers

PMID40508162
PMCPMC12155319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.