Evidence map›Paper›PMID 40508098›Full record

ArticleInternational journal of molecular sciences2025

Physiological Muscle Function Is Controlled by the Skeletal Endocannabinoid System in Murine Skeletal Muscles.

Nyamkhuu Ganbat, Zoltán Singlár, Péter Szentesi, Elena Lilliu, Zoltán Márton Kohler, László Juhász, Anikó Keller-Pintér, Xaver Koenig, Fabio Arturo Iannotti, László Csernoch and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nyamkhuu GanbatDepartment of Physiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0002-6949-0007
Zoltán SinglárDepartment of Physiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Péter SzentesiDepartment of Physiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0003-2621-2282
Elena LilliuDepartment of Neurophysiology and Neuropharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0009-0006-6346-4584
Zoltán Márton KohlerDepartment of Biochemistry, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0002-8299-105X
László JuhászInstitute of Surgical Research, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.
Anikó Keller-PintérDepartment of Biochemistry, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0002-4105-8458
Xaver KoenigDepartment of Neurophysiology and Neuropharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-2423-4966
Fabio Arturo IannottiInstitute of Biomolecular Chemistry (ICB), National Research Council of Italy (CNR), 80078 Pozzuoli, NA, Italy.ORCID 0000-0003-4480-8370
László CsernochDepartment of Physiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0002-2446-1456
Mónika SztretyeDepartment of Physiology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.ORCID 0000-0002-5946-6986

Funding

Hungarian National Research, Development and Innovation Office NKFIH-FK-142481, NKFIH 2019-2.1.11-TÉT-2019-00102National Research, Development, and Innovation Fund of Hungary TKP2020-NKA-04
6 · The paper itself

Abstract

The endocannabinoid system (ECS) is known to regulate crucial bodily functions, including healthy muscle activity. However, its precise roles in normal skeletal muscle function and the development of muscle disorders remain unclear. Previously, we developed a tamoxifen-inducible, skeletal muscle-specific CB

Indexed as

EndocannabinoidsMuscle, SkeletalAdenosine TriphosphateAnimalsCalciumMaleMembrane Potential, MitochondrialMiceMice, Inbred C57BLMitochondriaMuscle FatigueReceptor, Cannabinoid, CB1Adenosine TriphosphateCalciumEndocannabinoidsReceptor, Cannabinoid, CB1calcium homeostasisin vivo muscle forcemitochondrial respirationmurine skeletal muscleskeletal endocannabinoid systemstore-operated calcium entry

Identifiers

PMID40508098
PMCPMC12155153

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.