Evidence map›Paper›PMID 40508029›Full record

ReviewInternational journal of molecular sciences2025

Folate Receptor Alpha in Advanced Epithelial Ovarian Cancer: Diagnostic Role and Therapeutic Implications of a Clinically Validated Biomarker.

Gian Franco Zannoni, Angela Santoro, Antonio d'Amati, Nicoletta D'Alessandris, Giulia Scaglione, Belen Padial Urtueta, Michele Valente, Nadine Narducci, Francesca Addante, Saveria Spadola and 2 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gian Franco ZannoniPathology Unit, Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-4473-7560
Angela SantoroPathology Unit, Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-6964-5152
Antonio d'AmatiPathology Unit, Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-4810-1201
Nicoletta D'AlessandrisPathology Unit, Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-9580-6343
Giulia ScaglionePathology Unit, Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-9060-3854
Belen Padial UrtuetaPathology Unit, Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Michele ValentePathology Unit, Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Nadine NarducciPathology Unit, Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Francesca AddantePathology Unit, Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Saveria SpadolaDepartment of Medicine and Surgery, Kore University of Enna, 94100 Enna, Italy.ORCID 0000-0003-0387-5921
Emma BragantiniOspedale San Maurizio, 39100 Bolzano, Italy.
Giuseppe AngelicoDepartment of Medicine and Surgery, Kore University of Enna, 94100 Enna, Italy.ORCID 0000-0003-4808-2052

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Folate receptor alpha (FRα), a glycosylphosphatidylinositol-anchored glycoprotein encoded by the

Indexed as

Biomarkers, TumorCarcinoma, Ovarian EpithelialFolate Receptor 1Ovarian NeoplasmsAntibodies, Monoclonal, HumanizedFemaleHumansImmunoconjugatesImmunohistochemistryMaytansineAntibodies, Monoclonal, HumanizedBiomarkers, TumorFolate Receptor 1FOLR1 protein, humanImmunoconjugatesMaytansinemirvetuximab soravtansinefolate receptor alpha (FRα)immunohistochemistrymirvetuximab soravtansineovarian cancerplatinum-resistant epithelial ovarian cancer

Identifiers

PMID40508029
PMCPMC12154392

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.