Evidence map›Paper›PMID 40508007›Full record

ReviewInternational journal of molecular sciences2025

Plant-Fungi Mutualism, Alternative Splicing, and Defense Responses: Balancing Symbiosis and Immunity.

Xiaoqiong Zhao, Mehtab Muhammad Aslam, Moxian Chen, Debatosh Das

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Special Issue "Genetic Engineering of Plants for Stress Tolerance".International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoqiong ZhaoKey Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), Institute of Agro-Bioengineering, College of Life Sciences, Guizhou University, Guiyang 550025, China.ORCID 0000-0002-9786-7158
Mehtab Muhammad AslamDivision of Plant Sciences & Technology, College of Agriculture, Food and Natural Resources (CAFNR), University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0002-0890-4819
Moxian ChenState Key Laboratory of Green Pesticides, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang 550025, China.
Debatosh DasNatural Products Utilization Research, U.S. Department of Agriculture, Agricultural Research Service, Oxford, MS 38677, USA.ORCID 0000-0003-3729-5669

Funding

Frontiers Science Center for Asymmetric Synthesis and Medicinal Molecules, Department of Ed-ucation, Guizhou Province Qianjiaohe KY (2020)004Guizhou Provincial Basic Research Program (Natural Science)-ZK[2023]-099Hong Kong Research Grant Council AoE/M-403/16, GRF12100318, 12103219, 12103220, 12101722National Key Research and Development Program of China 2022YFD1700200National Natural Science Foundation of China 3201452Program of Introducing Talent to Chinese Universities 111 Program, D20023
6 · The paper itself

Abstract

Alternative splicing (AS) is the process of RNA maturation in eukaryotes, which is essential for post-transcriptional regulation. The transcripts produced by AS can encode distinct protein isoforms and contribute to the regulation of eukaryotic growth and development in response to a changing environment, and they are crucial in plant-fungal interactions. Plant-fungal symbiosis is one of the most significant biotic interactions in the biosphere. The symbiotic association of fungi not only improves plant growth and resistance but has potential significance for endangered species conservation and reproduction. Alternative splicing is involved in regulating symbiotic responses to host immune signals, regulating the host-symbiont contact, and initiating signaling during symbiosis. In recent years, mRNAs research has been progressing rapidly, and AS is an important post-transcriptional regulator that requires further investigation. However, while AS has been widely studied in mammalian disease research, very limited studies are available on the regulation of AS in plant-fungal symbiosis and their role in benefiting the interacting partners. In this review, we provide an overview of our existing knowledge about AS in symbiotic plant-fungal relationships and discuss potential hotspots for future investigation to expand our understanding of plant-fungal interactions.

Indexed as

Alternative SplicingFungiPlant ImmunityPlantsSymbiosisGene Expression Regulation, PlantPlant Diseasesalternative splicingmolecular mechanismsplant–fungal interactionspost-transcriptional regulationsmall molecules

Identifiers

PMID40508007
PMCPMC12155092

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.