ReviewInternational journal of molecular sciences2025
Circadian Disruption and Sleep Disorders in Astronauts: A Review of Multi-Disciplinary Interventions for Long-Duration Space Missions.
Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Circadian clock regulation of hemostasis: a systematic review of molecular pathways.Research and practice in thrombosis and haemostasis · 2026Pooled it
- Time-averaged simulated microgravity ameliorates tau-induced deficit in Drosophila melanogaster.NPJ microgravity · 2026Article
- Hypnogram-Driven Automatic Sleep Staging and a Quality-Index Assessment Through a Two-Stage LSTM-DNN Ensemble Learning Approach Using Multi-Biosignal Features for Sleep Disorder Detection.Sensors (Basel, Switzerland) · 2026Article
- Hardware-independent control for partial gravity simulation using a 2-DOF robotic device.Scientific reports · 2026Article
- Sensory Deprivation and the Brain: Neurobiological Mechanisms, Psychological Effects, and Clinical Implications.Brain sciences · 2026Review
- Monitoring and modulating interconnected physiological systems in space using portable closed-loop technologies.Frontiers in network physiology · 2026Article
- Physical Activity Guidelines for Astronauts: An Immunological Perspective.Biomolecules · 2025Review
- Space exploration and lifestyle medicine: a narrative review of its implications for astronaut health and remote Earth-based environments.Frontiers in physiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
As humanity advances into deep space exploration, astronauts on long-duration missions face significant challenges posed by circadian rhythm disruptions and sleep disorders, which arise from extreme environmental stressors such as microgravity, ionizing radiation, and operational workload. These disruptions not only compromise physiological and psychological health but also impair cognitive function and mission-critical performance. In this review, we summarized established countermeasures encompassing pharmacological interventions, light-based circadian regulation, and work-rest schedule optimization alongside innovative approaches such as gut microbiota modulation and traditional Chinese medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.