Evidence map›Paper›PMID 40507959›Full record

ArticleInternational journal of molecular sciences2025

MAPK15 Prevents

Monia Taranta, Sara Panepinto, Federico Galvagni, Lorenzo Franci, Mario Chiariello

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Monia TarantaIstituto di Fisiologia Clinica (IFC), Consiglio Nazionale delle Ricerche (CNR), 53100 Siena, Italy.ORCID 0009-0005-4245-2448
Sara PanepintoCore Research Laboratory (CRL), Istituto per lo Studio la Prevenzione e la Rete Oncologica (ISPRO), 53100 Siena, Italy.
Federico GalvagniDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-1967-9554
Lorenzo FranciIstituto di Fisiologia Clinica (IFC), Consiglio Nazionale delle Ricerche (CNR), 53100 Siena, Italy.ORCID 0000-0001-6300-1746
Mario ChiarielloIstituto di Fisiologia Clinica (IFC), Consiglio Nazionale delle Ricerche (CNR), 53100 Siena, Italy.ORCID 0000-0001-8434-5177

Funding

Next Generation EU Investment PE8 - Project Age-It: "Ageing Well in an Ageing Society"Regione Toscana/Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO)
6 · The paper itself

Abstract

Human type I interferons are crucial regulators of immune responses, essential for controlling infections and activating immune cells. Among them, Interferon Beta (IFNB1) plays a key role in inflammation, and its dysregulation is linked to various diseases, driving efforts to understand the molecular events governing its expression. Here, we identified Mitogen-Activated Protein Kinase 15 (MAPK15) as a novel regulator of

Indexed as

Interferon-betaJNK Mitogen-Activated Protein KinasesMAP Kinase Signaling SystemOxidative StressGene Expression RegulationHumansPromoter Regions, GeneticProto-Oncogene Proteins c-junInterferon-betaJNK Mitogen-Activated Protein KinasesProto-Oncogene Proteins c-juninflammationinterferonsMAP kinasessignal transduction

Identifiers

PMID40507959
PMCPMC12155439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.