Evidence map›Paper›PMID 40507950›Full record

ArticleInternational journal of molecular sciences2025

Novel Tetraene Macrodiolides Are Effective Inducers of Mitochondrial Apoptosis in Jurkat Cells.

Ilgiz I Islamov, Lilya U Dzhemileva, Ilgam V Gaisin, Alexey A Makarov, Usein M Dzhemilev, Vladimir A D'yakonov

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ilgiz I IslamovInstitute of Petrochemistry and Catalysis, Ufa Federal Research Centre, Russian Academy of Sciences, 141 Prospekt Oktyabrya, Ufa 450075, Russia.ORCID 0000-0002-7054-1369
Lilya U DzhemilevaN.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, Russia.ORCID 0000-0003-3315-4746
Ilgam V GaisinInstitute of Petrochemistry and Catalysis, Ufa Federal Research Centre, Russian Academy of Sciences, 141 Prospekt Oktyabrya, Ufa 450075, Russia.ORCID 0009-0001-5734-8150
Alexey A MakarovInstitute of Petrochemistry and Catalysis, Ufa Federal Research Centre, Russian Academy of Sciences, 141 Prospekt Oktyabrya, Ufa 450075, Russia.ORCID 0000-0001-7870-2334
Usein M DzhemilevN.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, Russia.ORCID 0000-0002-7992-6337
Vladimir A D'yakonovN.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, Russia.ORCID 0000-0002-7787-5054

Funding

Russian Science Foundation № 22-73-10164
6 · The paper itself

Abstract

We synthesized 16 representatives of a new class of tetraene macrodiolides with two pharmacophore

Indexed as

ApoptosisMitochondriaHEK293 CellsHumansJurkat Cells1,5-dienoic compoundsantitumor agentsapoptosiscyclocondensationhomo-cyclomagnesiationmacrodiolidestetraenes

Identifiers

PMID40507950
PMCPMC12155470

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.