ReviewInternational journal of molecular sciences2025
The Multifaceted Roles of Zinc Finger Proteins in Pluripotency and Reprogramming.
Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Comprehensive Pan-Cancer Analysis of ZNF668 Reveals the Prognostic and Immunological Significance of ZNF668.Current issues in molecular biology · 2025Article
- Targeting PURPL RNA enabled rejuvenation of senescence cells via epigenetic reprogramming.Journal of translational medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Zinc finger proteins (ZFPs) play a crucial role in regulating gene expression. In recent years, there has been increasing evidence highlighting the importance of zinc finger proteins in pluripotent stem cells, which hold great promise in regenerative medicine. The general mechanism by which zinc finger proteins function in gene regulation of pluripotent stem cells involves their interaction with core transcriptional regulatory networks. ZFPs can either enhance key pluripotency genes to maintain pluripotency or promote differentiation of stem cells towards specific lineages by suppressing these key pluripotency genes. Hence, understanding the role of ZFPs in pluripotency and reprogramming is crucial for unraveling the complex regulatory network that governs cell fate decisions. Here we provide a comprehensive review of the current knowledge regarding the multifaceted role of ZFPs in pluripotency maintenance and reprogramming. We propose that more efforts should be focused on fully understanding the fascinating functions of ZFPs in stem cell fate decision.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.