Evidence map›Paper›PMID 40507822›Full record

ArticleInternational journal of molecular sciences2025

Opioid-Induced Regulation of Cortical Circular-

Aria Gillespie, Stephanie E Daws

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aria GillespieDaws Laboratory, Center for Substance Abuse Research, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Stephanie E DawsDaws Laboratory, Center for Substance Abuse Research, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.

Funding

TRAINING PROGRAM: DRUGS OF ABUSE RELATED NEUROPEPTIDEST32DA007237 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI ELLEN M UNTERWALD · 1988 to 2026
$10.6M
Circular RNA signaling in opioid seeking phenotypesDP1DA051550 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI DAWS, STEPHANIE · 2020 to 2024
$2.4M
NIDA NIH HHS DP1 DA051550NIDA NIH HHS T32 DA007237NIH HHS 1DP1DA051550-25A5
6 · The paper itself

Abstract

Opioid use induces neurobiological adaptations throughout mesolimbic brain regions, such as the orbitofrontal cortex (OFC), which mediates decision-making and emotional-cognitive regulation. Previously, we showed that a circular RNA (circRNA) species, rno_

Indexed as

Analgesics, OpioidGene Expression RegulationMicroRNAsReceptors, N-Methyl-D-AspartateRNA, CircularAnimalsHeroinMaleMorphinePrefrontal CortexRatsRats, Sprague-DawleyAnalgesics, OpioidHeroinMicroRNAsMorphineNR2B NMDA receptorReceptors, N-Methyl-D-AspartateRNA, Circularcircular RNAmicroRNAmorphineopioidssplicing

Identifiers

PMID40507822
PMCPMC12154416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.