Evidence map›Paper›PMID 40507808›Full record

ArticleInternational journal of molecular sciences2025

The Effects and Mechanisms of Continuous 7-Day Hypobaric Hypoxia Exposure on Sleep Architecture in Rats.

Fang Li, Xianxie Zhang, Anping Ye, Ling Qi, Tianke Huang, Xitai Chen, Maoxing Li, Chengrong Xiao, Yuguang Wang, Yue Gao and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fang LiSchool of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Xianxie ZhangDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.ORCID 0000-0003-3166-3694
Anping YeDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Ling QiSchool of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Tianke HuangSchool of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Xitai ChenSchool of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Maoxing LiDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Chengrong XiaoDepartment of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Yuguang WangSchool of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Yue GaoSchool of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Zengchun MaSchool of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-altitude environments pose significant risks for insomnia development, which severely compromises both physiological health and occupational performance. To elucidate the mechanisms underlying altitude-induced sleep disruption and establish a validated animal model for therapeutic intervention development, we exposed Sprague-Dawley rats to hypobaric hypoxia (5500 m altitude equivalent: 308 mmHg, 20.37% O

Indexed as

HypoxiaSleepAltitudeAnimalsCircadian RhythmDisease Models, AnimalMaleRatsRats, Sprague-DawleyWakefulnessplateau insomniarat modelsleep rhythm and homeostasiswireless EEG telemetry

Identifiers

PMID40507808
PMCPMC12155171

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.