ArticleInternational journal of molecular sciences2025
Low Efficiency of Homology-Independent Targeted Integration for CRISPR/Cas9 Correction in the Vicinity of the
Chang-Han Ho, Cheng-Yu Tsai, Chi-Chieh Chang, Chin-Ju Hu, Cheng-Yen Huang, Ying-Chang Lu, Pei-Hsuan Lin, Chin-Hsien Lin, Han-I Lin, Chih-Hsin OuYang and 6 more
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In one paragraphArticle in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
16 authors.
Chang-Han HoDepartment of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei 100225, Taiwan.ORCID 0009-0007-3299-6657 Cheng-Yu TsaiDepartment of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei 100225, Taiwan.ORCID 0000-0001-6150-4577 Chi-Chieh ChangDepartment of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei 100225, Taiwan.ORCID 0000-0002-0783-2868 Chin-Ju HuDepartment of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei 100225, Taiwan.ORCID 0000-0002-3170-9691 Cheng-Yen HuangGene Knockout/in Cell Line Modeling Core, Human Disease Modeling Center, First Core Laboratory, Branch Office of Research and Development, National Taiwan University College of Medicine, Taipei 100233, Taiwan.
Ying-Chang LuDepartment of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei 100225, Taiwan.
Pei-Hsuan LinDepartment of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei 100225, Taiwan.
Chin-Hsien LinDepartment of Neurology, National Taiwan University Hospital, Taipei 100225, Taiwan.
Han-I LinDepartment of Neurology, National Taiwan University Hospital, Taipei 100225, Taiwan.
Chih-Hsin OuYangDepartment of Neurology, National Taiwan University Hospital, Taipei 100225, Taiwan.
Chuan-Jen HsuDepartment of Otolaryngology-Head and Neck Surgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427, Taiwan.ORCID 0000-0002-7548-7736 Tien-Chen LiuDepartment of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei 100225, Taiwan.ORCID 0000-0001-6771-5025 You-Tzung ChenGraduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine, Taipei 100233, Taiwan.ORCID 0000-0001-6510-3420 Yen-Hui ChanDepartment of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei 100225, Taiwan.
Yen-Fu ChengDepartment of Medical Research, Taipei Veterans General Hospital, Taipei 112201, Taiwan.ORCID 0000-0003-1995-5854 Chen-Chi WuDepartment of Otolaryngology-Head and Neck Surgery, National Taiwan University Hospital, Taipei 100225, Taiwan.ORCID 0000-0002-5047-2204 Funding
National Science and Technology Council of Taiwan 107-2622-B-002-008-CC2National Taiwan University Hospital 106-T04
6 · The paper itselfAbstract
Indexed as
CRISPR-Cas SystemsGene EditingHearing Loss, SensorineuralMembrane Transport ProteinsSulfate TransportersGoiter, NodularHumansMembrane Transport ProteinsSLC26A4 protein, humanSulfate TransportersCRISPR/Cas9gene editinghearing losshomology-independent targeted integrationPendred syndromeSLC26A4
Identifiers
PMID40507794
PMCPMC12155412
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