Evidence map›Paper›PMID 40507651›Full record

ReviewJournal of clinical medicine2025

Etrasimod: Modulating Sphingosine-1-Phosphate Receptors to Treat Ulcerative Colitis.

Cristina Martinez-Molina, Begoña González-Suárez

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Cristina Martinez-MolinaDepartment of Pharmacy, Division of Medicines, Hospital Clínic de Barcelona, Villarroel 170, 08036 Barcelona, Spain.ORCID 0000-0001-5079-613X
Begoña González-SuárezEndoscopy Unit, Department of Gastroenterology, Clinical Institute of Digestive and Metabolic Diseases (ICMDM), Hospital Clínic de Barcelona, Villarroel 170, 08036 Barcelona, Spain.ORCID 0000-0001-9566-5993

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aimed to provide a comprehensive overview of the current landscape of etrasimod. Etrasimod is an oral, once-daily selective modulator of sphingosine 1-phosphate receptors (S1PR), developed for the treatment of moderately to severely active ulcerative colitis and currently being explored for its potential in other immune-mediated inflammatory diseases. It selectively targets the S1PR subtypes S1PR

Indexed as

etrasimodgastroenterologyimmune-mediated diseaseinflammatory bowel diseasesphingosine-1-phosphate receptorulcerative colitis

Identifiers

PMID40507651
PMCPMC12155636

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.