Evidence map›Paper›PMID 40507536›Full record

ArticleJournal of clinical medicine2025

Randomized, Cross over, Multicenter, Single-Blind Study Comparing Citicoline 500 mg/Homotaurine 50 mg/Vitamin B3 54 mg/Pyrroloquinoline Quinone 5 mg (Neuprozin Mito

Gemma Caterina Maria Rossi, Michele Rinaldi, Francesco Matarazzo, Diego Strianese, Giuseppe Campagna, Michele La Ragione, Paolo Esposito Veneruso, Giovanni Scapagnini, Ciro Costagliola

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Pyrroloquinoline Quinone and NADPharmaceuticals (Basel, Switzerland) · 2026
    Review
  2. Vitamins and nutraceuticals in glaucoma research.European journal of ophthalmology · 2026
    Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gemma Caterina Maria RossiDepartment of Surgical Sciences, University Eye Clinic, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.ORCID 0000-0003-3519-2420
Michele RinaldiDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples "Federico II", 80131 Naples, Italy.
Francesco MatarazzoDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0002-2614-0234
Diego StrianeseDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0002-6140-7539
Giuseppe CampagnaDepartment of Medical-Surgical Sciences and Translational Medicine, University of Rome "Sapienza", 00185 Roma, Italy.ORCID 0000-0002-1884-9171
Michele La RagioneDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples "Federico II", 80131 Naples, Italy.
Paolo Esposito VenerusoDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples "Federico II", 80131 Naples, Italy.
Giovanni ScapagniniDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0003-1592-5586
Ciro CostagliolaDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0001-8477-6188

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

citicolineglaucomahomotaurineneuroprotectionpattern electroretinogrampyrroloquinoline quinonequality of lifevisual field

Identifiers

PMID40507536
PMCPMC12155607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.