Evidence map›Paper›PMID 40507347›Full record

ArticleCancers2025

A High Performing Biomarker Signature for Detecting Early-Stage Pancreatic Ductal Adenocarcinoma in High-Risk Individuals.

Norma A Palma, Aimee L Lucas, Bryson W Katona, Alcibiade Athanasiou, Natasha M Kureshi, Lisa Ford, Thomas Keller, Stephen Weber, Ralph Schiess, Thomas King and 2 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Personalizing CA125 Levels Using Tumor Marker Variants: A Case-Control Analysis of Diagnostic Performance for Pancreatic Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  5. Article
  6. Challenges of early detection of pancreatic cancer.The Journal of clinical investigation · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Norma A PalmaImmunovia, Inc., Durham, NC 27713, USA.ORCID 0000-0001-6900-0533
Aimee L LucasDivision of Gastroenterology and Hepatology, Mount Sinai West and Sinai Morningside Hospitals, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-0341-4826
Bryson W KatonaDepartment of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.ORCID 0000-0001-8186-9119
Alcibiade AthanasiouProteomedix AG, 8952 Schlieren, Switzerland.ORCID 0000-0002-8145-8325
Natasha M KureshiImmunovia, Inc., Durham, NC 27713, USA.
Lisa FordImmunovia, Inc., Durham, NC 27713, USA.
Thomas KellerACOMED Statistic, 04109 Leipzig, Germany.ORCID 0000-0001-8160-3046
Stephen WeberACOMED Statistic, 04109 Leipzig, Germany.
Ralph SchiessProteomedix AG, 8952 Schlieren, Switzerland.
Thomas KingImmunovia, Inc., Durham, NC 27713, USA.ORCID 0009-0006-8581-5824
Diane M SimeoneDepartment of Surgery, University of California, San Diego Health, Moores Cancer Center, San Diego, CA 92037, USA.
Randall BrandDivision of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.ORCID 0000-0002-4136-3313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkersfamilial pancreatic cancergermline mutationshigh-riskpancreatic ductal adenocarcinomapotentially resectablesurveillance

Identifiers

PMID40507347
PMCPMC12153528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.