Evidence map›Paper›PMID 40507269›Full record

ReviewCancers2025

Suicidal Ideation, Suicide Attempts, and Suicide Mortality in Cancer: An Overview of Systematic Reviews with Meta-Analysis.

Javier Martinez-Calderon, Marta Infante-Cano, Javier Matias-Soto, Alejandro Galan-Mercant, Saul Pineda-Escobar, Olga Villar-Alises, Veronica Perez-Cabezas, Cristina Garcia-Muñoz, Juan-Carlos Hernandez-Rodriguez

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Javier Martinez-CalderonInstituto de Biomedicina de Sevilla-IBiS (Hospitales Universitarios Virgen del Rocío y Macarena, CSIC, Universidad de Sevilla), 41013 Sevilla, Spain.
Marta Infante-CanoCTS 1110: Uncertainty, Mindfulness, Self, and Spirituality (UMSS) Research Group, 41009 Andalusia, Spain.
Javier Matias-SotoCTS 1110: Uncertainty, Mindfulness, Self, and Spirituality (UMSS) Research Group, 41009 Andalusia, Spain.ORCID 0000-0002-9277-9933
Alejandro Galan-MercantDepartment of Nursing and Physiotherapy, University of Cadiz, 11009 Cadiz, Spain.ORCID 0000-0003-3581-0372
Saul Pineda-EscobarDepartment of Physiotherapy, Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, 41009 Seville, Spain.ORCID 0000-0001-6228-2734
Olga Villar-AlisesDepartment of Physiotherapy, Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, 41009 Seville, Spain.
Veronica Perez-CabezasDepartment of Nursing and Physiotherapy, University of Cadiz, 11009 Cadiz, Spain.ORCID 0000-0002-3896-357X
Cristina Garcia-MuñozCTS 1110: Uncertainty, Mindfulness, Self, and Spirituality (UMSS) Research Group, 41009 Andalusia, Spain.ORCID 0000-0003-2621-2098
Juan-Carlos Hernandez-RodriguezDermatology Department, Virgen del Rocío University Hospital, 41013 Seville, Spain.ORCID 0000-0003-2525-4069

Funding

Erasmus+ Strategic Partnership for Higher Education Program (KA220-HED-99E45528)
6 · The paper itself

Abstract

backgroundthis overview of systematic reviews with meta-analysis summarized the epidemiology of suicide in cancer, mainly focused on prevalence, incidence, and risk.

methodsthe CINAHL (via EBSCOhost), Embase, PsycINFO (via ProQuest), and PubMed databases were searched from inception to February 2024. AMSTAR 2 evaluated the methodological quality of reviews. The degree of overlap between reviews was calculated.

resultsTwelve systematic reviews with meta-analysis were included. The prevalence of suicidal ideation in prostate cancer was 9.85% (95%CI 7.31-12.70%). The relative risk of suicidal ideation in prostate cancer was 2.01 (95%CI: 1.52-2.64) in comparison to controls without this type of cancer during the first 12 months after diagnosis. Furthermore, the risk of suicidal ideation was higher among individuals with bladder cancer in comparison to people without this clinical condition (HR 1.90, 95%CI 1.29-2.81). The crude suicide mortality rate per 100,000 person-years in prostate cancer was 47.1 per 100,000 person-years (95%CI 39.85-54.96). Incidence suicide death per 100,000 person-years was higher in sarcoma (60.99 per 100,000 person-years, 95%CI 17.37-214.19), esophagus (87.71 per 100,000 person-years, 95%CI 27.42-280.54), and pancreas (75.39 per 100,000 person-years, 95%CI 41.80-135.97). Finally, the standardized mortality ratio by suicide was higher in the pancreas (SMR 6.42, 95%CI 1.60-25.76), bone and cartilage (SMR 9.59, 95%CI 1.54-59.77), and mesothelioma (SMR 13.07, 95%CI 1.61-105.80).

conclusionsoverall, meta-analyses underlined the relevance of suicide mortality in different cancer sites and geographical regions. Some meta-analyses also found suicidal ideation may be important in prostate or bladder cancer.

Indexed as

cancerincidenceoverviewprevalencesuicidesystematic review

Identifiers

PMID40507269
PMCPMC12153619

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.