Evidence map›Paper›PMID 40507236›Full record

ArticleCancers2025

Cardiovascular Safety Profile of BRAF and MEK Inhibitors in Melanoma: FAERS Data Through a Retrospective Disproportionality Analysis (2014-2023).

Maria Antonietta Barbieri, Giulia Russo, Giuseppe Cicala, Concetta Zito, Edoardo Spina, Nicola Silvestris, Mariacarmela Santarpia

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria Antonietta BarbieriDepartment of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-2019-4696
Giulia RussoDepartment of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.ORCID 0009-0002-1681-1417
Giuseppe CicalaDepartment of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.
Concetta ZitoDepartment of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-6908-4316
Edoardo SpinaDepartment of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-2509-7449
Nicola SilvestrisMedical Oncology Department, IRCCS Istituto Tumori "Giovanni Paolo II", 70124 Bari, Italy.ORCID 0000-0001-7814-7318
Mariacarmela SantarpiaMedical Oncology Unit, Department of Human Pathology in Adulthood and Childhood "Gaetano Barresi", University of Messina, 98125 Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BRAF inhibitorscardiovascular toxicitydisproportionality analysisFAERSMEK inhibitorsmelanoma

Identifiers

PMID40507236
PMCPMC12153699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.