Evidence map›Paper›PMID 40507149›Full record

ArticleNutrients2025

Poor Appetite and Survival in Patients Admitted to an Acute Palliative Care Unit for Comprehensive Palliative Care.

Sebastiano Mercadante, Daniele Napolitano, Alessio Lo Cascio, Stefano Mancin, Alessandra Casuccio

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sebastiano MercadanteMain Regional of Supportive/Palliative Care, La Maddalena Cancer Center, 90146 Palermo, Italy.ORCID 0000-0001-9859-6487
Daniele NapolitanoCEMAD, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Roma, Italy.ORCID 0000-0003-2481-5354
Alessio Lo CascioDirection of Health Professions, La Maddalena Cancer Center, 90146 Palermo, Italy.ORCID 0000-0001-5581-4114
Stefano MancinIRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy.ORCID 0000-0002-4988-4391
Alessandra CasuccioDepartment of Health Promotion, Maternal and Infant Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-5676-9535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesLoss of appetite is a common symptom in patients with advanced cancer, and may contribute to patient deterioration. There is a lack of information about this issue, particularly in patients with advanced cancer admitted to an acute palliative care unit. The aims of this study were to assess appetite loss in patients admitted to an APCU and to investigate whether changes following comprehensive palliative care treatment are associated with survival. MATERIALS AND

methodsA consecutive sample of 520 patients admitted to the APCU was assessed. Patient characteristics and Edmonton Symptom Assessment Scale (ESAS) were measured at admission (T0) and after one week of comprehensive palliative care treatment (T7).

resultsOf 381 patients screened, 208 (54.6%) had a poor appetite rating (≥4/10). Following comprehensive palliative care (T7), the number of patients with poor appetite significantly decreased to 116 (30%) (

conclusionsA large proportion of patients admitted to an APCU present moderate-to-severe poor appetite. Clinical improvement of poor appetite is associated with improved survival.

Indexed as

AppetiteNeoplasmsPalliative CareAgedAged, 80 and overFemaleHumansMaleMiddle Agedacute palliative care unitadvanced cancerpalliative carepoor appetitesurvival

Identifiers

PMID40507149
PMCPMC12157299

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.