Evidence map›Paper›PMID 40507117›Full record

ArticleNutrients2025

Daily Administration of Agmatine Reduced Anxiety-like Behaviors and Neural Responses in the Brains of Male Mice with Persistent Inflammation in the Craniofacial Region.

Yuya Iwamoto, Kajita Piriyaprasath, Andi Sitti Hajrah Yusuf, Mana Hasegawa, Yoshito Kakihara, Tsutomu Sato, Noritaka Fujii, Kensuke Yamamura, Keiichiro Okamoto

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuya IwamotoDivision of Oral Physiology, Faculty of Dentistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8514, Japan.ORCID 0009-0009-1396-3192
Kajita PiriyaprasathDepartment of Restorative Dentistry, Faculty of Dentistry, Naresuan University, Phitsanulok 650000, Thailand.ORCID 0000-0003-0141-796X
Andi Sitti Hajrah YusufDivision of Oral Physiology, Faculty of Dentistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8514, Japan.
Mana HasegawaDivision of Oral Physiology, Faculty of Dentistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8514, Japan.ORCID 0000-0003-1642-1371
Yoshito KakiharaDivision of Dental Pharmacology, Faculty of Dentistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8514, Japan.ORCID 0000-0002-6014-8707
Tsutomu SatoSakeology Center, Niigata University, Niigata 950-2181, Japan.
Noritaka FujiiDivision of Dental Clinical Education, Faculty of Dentistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8514, Japan.ORCID 0000-0002-4148-7105
Kensuke YamamuraDivision of Oral Physiology, Faculty of Dentistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8514, Japan.ORCID 0000-0002-4797-6874
Keiichiro OkamotoDivision of Oral Physiology, Faculty of Dentistry, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8514, Japan.ORCID 0000-0002-3519-9561

Funding

JSPS KAKENHI and Pioneering Research Initiated by the Next Generation JP23K09391 and J24H0003
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgmatineAnxietyBehavior, AnimalBrainInflammationAnimalsDisease Models, AnimalFreund's AdjuvantMaleMiceMice, Inbred C57BLProto-Oncogene Proteins c-fosAgmatineFreund's AdjuvantProto-Oncogene Proteins c-fosanxietycraniofacial tissuesepigenetic changeinflammation

Identifiers

PMID40507117
PMCPMC12158226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.