Evidence map›Paper›PMID 40507093›Full record

ArticleNutrients2025

In Preclinical Epilepsy, GLUT1 and GFAP Dysregulation in Cells Surrounding the Third Ventricle, Including Tanycytes, Is Differentially Restored with Ketogenic Diet Treatment.

Parisa Rafiei, Huda S Mian, Shruthi H Iyer, Samantha B Draves, Stephanie A Matthews, Daniel E Rendon, Emma J Neesen, Madeline Dunlay, McKenna Revis, Adrianna L Glisan and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Parisa RafieiDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Huda S MianDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Shruthi H IyerDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Samantha B DravesDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Stephanie A MatthewsDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Daniel E RendonDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Emma J NeesenDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Madeline DunlayDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
McKenna RevisDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Adrianna L GlisanDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.
Timothy A SimeoneDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.ORCID 0000-0002-8716-7211
Kristina A SimeoneDepartment of Pharmacology & Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.ORCID 0000-0001-5072-3694

Funding

Autoresuscitation and SUDEPR01NS126418 · NINDS · CREIGHTON UNIVERSITY · PI Kristina A Simeone, Timothy A. Simeone · 2022 to 2026
$1.7M
Replacing an Animal Resource Facility Cage Washer.G20RR024001 · NCRR · CREIGHTON UNIVERSITY · PI DRESCHER, KRISTEN · 2007 to 2007
$638k
Mechanisms of SUDEP: Failure to AutoresuscitateR21NS111389 · NINDS · CREIGHTON UNIVERSITY · PI SIMEONE, KRISTINA A · 2020 to 2020
$400k
Creighton University LB692NCRR NIH HHS G20 RR024001Nebraska State Biomedical Research Resources grant G20RR024001NIH HHS 1R01NS126418-01A1NINDS NIH HHS R01 NS126418NINDS NIH HHS R21 NS111389NINDS NIH HHS R21NS111389
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diet, KetogenicEpendymoglial CellsEpilepsyGlial Fibrillary Acidic ProteinGlucose Transporter Type 1Third VentricleAnimalsDisease Models, AnimalDoublecortin Domain ProteinsDoublecortin ProteinMaleMiceMice, KnockoutMicrotubule-Associated ProteinsDcx protein, mouseDoublecortin Domain ProteinsDoublecortin ProteinGlial Fibrillary Acidic Proteinglial fibrillary astrocytic protein, mouseGlucose Transporter Type 1Microtubule-Associated ProteinsSlc2a1 protein, mouseDCXepilepsyGFAPGLUT1hypothalamusKcna1-null mouseketogenic dietKv1.1 knockout mousemetabolic therapyseizuretanycyte

Identifiers

PMID40507093
PMCPMC12157610

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.