Evidence map›Paper›PMID 40507015›Full record

ArticleDiagnostics (Basel, Switzerland)2025

B-Cell Epitope Mapping of the

Jessica L Keane, Mahashweta Bose, Barbara J Molini, Kelika A Konda, Silver K Vargas, Michael Reyes Diaz, Carlos F Caceres, Jeffrey D Klausner, Rebecca S Treger, Lorenzo Giacani

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Participants inFrontiers in immunology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jessica L KeaneDepartment of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Harborview Medical Center, 300 9th Ave, Seattle, WA 98104, USA.ORCID 0009-0008-2632-0762
Mahashweta BoseDepartment of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Harborview Medical Center, 300 9th Ave, Seattle, WA 98104, USA.ORCID 0000-0001-6872-5591
Barbara J MoliniDepartment of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Harborview Medical Center, 300 9th Ave, Seattle, WA 98104, USA.
Kelika A KondaKeck School of Medicine, University of Southern California, 1975 Zonal Ave, Los Angeles, CA 90033, USA.ORCID 0000-0003-2836-0174
Silver K VargasCenter for Interdisciplinary Studies in Sexuality, AIDS and Society, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, Lima 15102, Peru.
Michael Reyes DiazCenter for Interdisciplinary Studies in Sexuality, AIDS and Society, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, Lima 15102, Peru.
Carlos F CaceresCenter for Interdisciplinary Studies in Sexuality, AIDS and Society, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, Lima 15102, Peru.
Jeffrey D KlausnerKeck School of Medicine, University of Southern California, 1975 Zonal Ave, Los Angeles, CA 90033, USA.
Rebecca S TregerDepartment of Laboratory Medicine and Pathology, University of Washington, 1959 NE Pacific St., Seattle, WA 98195, USA.ORCID 0000-0002-2736-3341
Lorenzo GiacaniDepartment of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Harborview Medical Center, 300 9th Ave, Seattle, WA 98104, USA.ORCID 0000-0003-3889-7274

Funding

University of Washington (UW) Sexually Transmitted Infections (STI) Cooperative Research Center (CRC) - Syphilis Vaccine to Protect against Local and Disseminated T. pallidum InfectionU19AI144133 · NIAID · UNIVERSITY OF WASHINGTON · PI WALD, ANNA · 2019 to 2023
$10.6M
Syphilis Immunology and Biology to Improve Clinical Management and Vaccine DesignR01AI139265 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jeffrey David Klausner · 2018 to 2026
$4.8M
NIAID NIH HHS R01 AI139265NIAID NIH HHS R01AI139265NIAID NIH HHS U19 AI144133NIAID NIH HHS U19AI144133
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

epitope mappingsyphilisTp0435 lipoproteinTreponema pallidum

Identifiers

PMID40507015
PMCPMC12154512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.