Evidence map›Paper›PMID 40506765›Full record

ArticleChinese medicine2025

Study on a Traditional Chinese Medicine constitution recognition model using tongue image characteristics and deep learning: a prospective dual-center investigation.

Yongyue Liu, Linmiao Fan, Mei Zhao, Dongshen Wei, Menglan Zhao, Yihang Dong, Xiaoqing Zhang

Abstract read
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Article in Chinese medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yongyue Liu *School of Life Sciences, Beijing University of Chinese Medicine, No. 11, North 3rd Ring Road East, Beijing, 100029, China.
Linmiao Fan *School of Life Sciences, Beijing University of Chinese Medicine, No. 11, North 3rd Ring Road East, Beijing, 100029, China.
Mei ZhaoSchool of Life Sciences, Beijing University of Chinese Medicine, No. 11, North 3rd Ring Road East, Beijing, 100029, China.
Dongshen WeiSchool of Life Sciences, Beijing University of Chinese Medicine, No. 11, North 3rd Ring Road East, Beijing, 100029, China.
Menglan ZhaoSchool of Life Sciences, Beijing University of Chinese Medicine, No. 11, North 3rd Ring Road East, Beijing, 100029, China.
Yihang DongSchool of Life Sciences, Beijing University of Chinese Medicine, No. 11, North 3rd Ring Road East, Beijing, 100029, China.
Xiaoqing ZhangSchool of Life Sciences, Beijing University of Chinese Medicine, No. 11, North 3rd Ring Road East, Beijing, 100029, China. 202001003@bucm.edu.cn.ORCID http://orcid.org/0000-0002-2195-9574

Funding

Beijing University of Chinese Medicine BZY-BZX-2022-04Key Technologies Research and Development Program 2022YFC3502300Key Technologies Research and Development Program 2022YFC3502301the State Administration of Traditional Chinese Medicine zyyzdxk-2023263
6 · The paper itself

Abstract

purposeThe objective of this study was to develop a quantitatively analyzed Traditional Chinese Medicine (TCM) constitution recognition model utilizing tongue fusion features and deep learning techniques.

methodsA prospective investigation was conducted on participants undergoing TCM constitution assessment at two medical centers. Tongue images and corresponding TCM constitution data were collected from 1374 participants using specialized equipment. Both traditional and deep features were extracted from these images. Significant features associated with constitutional characteristics were identified through LASSO regression and Random Forest (RF). Eight machine learning algorithms were employed to construct and evaluate the efficacy of the models. The highest-performing model was selected as the foundational classifier for developing an integrated tongue image feature model. Model performance was comprehensively evaluated using accuracy, precision, recall, F1 score, and area under the curve (AUC).

resultsAnalysis revealed 11 critical traditional tongue image features and 26 deep tongue image features. Three datasets were constructed: traditional tongue image features, deep tongue image features, and a fusion feature dataset incorporating both. The multilayer perceptron (MLP) model combining traditional and deep features demonstrated superior performance in TCM constitution classification compared to single-feature models. In the training phase, the model achieved an accuracy (ACC) of 0.893 and an AUC of 0.948. On the test set, it achieved an ACC of 0.837 and an AUC of 0.898, with sensitivity and specificity of 0.680 and 0.930, respectively, indicating excellent generalization ability.

conclusionsThis study successfully developed an intelligent TCM constitution recognition model that overcomes the limitations of traditional methods and validates the value of tongue images for accurate constitution recognition.

Indexed as

Deep learningNeural networkTCM constitutionTongue diagnosis

Identifiers

PMID40506765
PMCPMC12160370

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