Evidence map›Paper›PMID 40506754›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2025

Image analysis:

Joel Wessendorf, Anna-Maria Spektor, Brahim Aboulmaouahib, Johanna Daum, Frederik M Glatting, Kai Schlamp, Matthias Grott, Florian Eichhorn, Claus Peter Heußel, Hans Ulrich Kauczor and 5 more

Abstract read
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Diagnostic performance of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Review
  4. Bridging Research and Clinical Practice: Automated [Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joel WessendorfDepartment of Nuclear Medicine, University Hospital Mainz, Langenbeckstraße 1, 55131, Mainz, Germany. joel.wessendorf@unimedizin-mainz.de.ORCID http://orcid.org/0009-0007-0273-2183
Anna-Maria SpektorDepartment of Nuclear Medicine, University Hospital Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Brahim AboulmaouahibInstitute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.
Johanna DaumDepartment of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Frederik M GlattingDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Kai SchlampDepartment of Radiology, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany.
Matthias GrottTranslational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.
Florian EichhornTranslational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.
Claus Peter HeußelDepartment of Radiology, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany.
Hans Ulrich KauczorTranslational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.
Michael KreuterMainz Center for Pulmonary Medicine, Department of Pneumology, Department of Pulmonary, Critical Care & Sleep Medicine, Mainz University Medical Center, Marienhaus Clinic Mainz, Mainz, Germany.
Mathias SchreckenbergerDepartment of Nuclear Medicine, University Hospital Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.
Hauke WinterTranslational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.
Uwe HaberkornDepartment of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany.
Manuel RöhrichDepartment of Nuclear Medicine, University Hospital Mainz, Langenbeckstraße 1, 55131, Mainz, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary lesions inconclusive in MATERIALS AND

methods20 histologically confirmed pulmonary lesions (13 lung cancer, 7 benign) in 19 patients were evaluated. All patients underwent an inconclusive

resultsThe texture parameters HIST Maximum grey level (AUC = 0.901), HIST Mean (AUC = 0.802), HIST Mode (AUC = 0.835), HIST Range (AUC = 0.901) and GLCM Information correlation 1 (AUC = 0.824) showed significant differences between lung cancer and benign pulmonary lesions. AUC values of conventional parameters (SUVmax, SUVmean, TBR(SUVmax), TBR(SUVmean)) were 0.791, 0.868, 0.802 and 0.857, respectively. Maximum AUC values of bivariable logistic regression were 0.967 and 0.978 for two texture parameters and the combination of conventional and texture parameters, respectively. Correlations between texture parameter pairs were mainly moderate (0.4≤ρ≤0.59). 2/5 texture parameters (HIST Mean, HIST Mode) displayed no very strong correlations (0.8≤ρ≤1.00) to any conventional parameters or lesion volume.

conclusion

Indexed as

Gallium RadioisotopesLung NeoplasmsPositron Emission Tomography Computed TomographyAdultAgedAged, 80 and overDiagnosis, DifferentialFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedRadiopharmaceuticalsFluorodeoxyglucose F18Gallium RadioisotopesRadiopharmaceuticalsImage analysisLung cancerPulmonary lesionTexture analysis

Identifiers

PMID40506754
PMCPMC12164081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.