Evidence map›Paper›PMID 40506745›Full record

ArticleJournal of medical case reports2025

Examination of a patient with renal tubular acidosis: renal tubular acidosis with hyperparathyroidism, pheochromocytoma, and multiple kidney stones: a case report.

Marzieh Nasiri Sangari, Reza Salehinia, Hossein Rahnama, Fatemeh Ameri, Arefeh Azimi Athary, Farnaz Lashgari

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Marzieh Nasiri SangariDepartment of Surgical Technology, Tabas School of Nursing, Birjand University of Medical Sciences, Birjand, Iran.
Reza SalehiniaDepartment of Surgical Technology, Tabas School of Nursing, Birjand University of Medical Sciences, Birjand, Iran. rezaotg@gmail.com.
Hossein RahnamaSeyyed Mostafa Khomeini Hospital, Taba's City, Brigand University of Medical Sciences, Brigand, Iran.
Fatemeh AmeriStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.
Arefeh Azimi AtharyStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.
Farnaz LashgariStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal tubular acidosis is a rare disorder affecting acid-base balance, and its coexistence with endocrine abnormalities such as hyperparathyroidism and pheochromocytoma is exceptionally uncommon. This combination presents unique diagnostic and therapeutic challenges requiring a multidisciplinary approach. CASE PRESENTATION: A 25-year-old Iranian woman presented with recurrent flank pain, episodic palpitations, headaches, and intermittent hypertension. Imaging revealed bilateral nephrolithiasis, leading to ureteroscopic lithotripsy. Biochemical evaluation confirmed distal renal tubular acidosis (type 1), hyperparathyroidism, and pheochromocytoma, a rare and complex association. Metabolic acidosis, hypokalemia, and elevated catecholamine metabolites were noted. Potassium citrate was prescribed for stone prevention, and the patient remains asymptomatic after a year of follow-up.

conclusionThis case underscores the need for heightened clinical suspicion when nephrolithiasis is accompanied by systemic symptoms. The rare coexistence of renal tubular acidosis, hyperparathyroidism, and pheochromocytoma highlights the importance of early recognition and a multidisciplinary approach to prevent complications and optimize patient outcomes.

Indexed as

Acidosis, Renal TubularAdrenal Gland NeoplasmsHyperparathyroidismKidney CalculiPheochromocytomaAdultFemaleHumansLithotripsyPotassium CitratePotassium CitrateAcidosisRenalTubular

Identifiers

PMID40506745
PMCPMC12164118

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