SynthesisAdvances in therapy2025
Systematic Review of the Use of the WHO-5 Well-Being Index Across Different Disease Areas.
Synthesis in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The trial behind it
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Who cites it
22 citing papers in PubMed.
- Peripheral BDNF-TrkB Expression and Vitamin D Status in Depression, Prediabetes and Type 2 Diabetes: A Cross-Sectional Biomarker Study.Biomedicines · 2026Article
- Well-being differences and changes in people with somatic and psychiatric disorders or multimorbidities: modelling COVID-19 as a global natural experiment of stress vulnerability.BMJ mental health · 2026Article
- Article
- Mental Health and Health-Related Behavioral Patterns Surrounding a Major International Sporting Event: An Observational Study.Diseases (Basel, Switzerland) · 2026Article
- Mapping Conditional Associations Among Wellbeing, Distress, Spirituality, and Yoga Practice: A Network Analysis.Healthcare (Basel, Switzerland) · 2026Article
- Nonverbal AI-Based Communication Robot for Staff in Disaster-Affected Care Facilities: Exploratory ABAB Intervention Study.JMIR formative research · 2026Article
- Article
- Gendered patterns of common mental health outcomes and suicidal ideation after suicide bereavement and the role of perceived social support.Health promotion international · 2026Article
- Post-COVID-19 Consequences and Psychological Well-Being in Students: The Mediating Role of Trait Anxiety.Behavioral sciences (Basel, Switzerland) · 2026Article
- Psychosocial Outcomes in Telemedicine and Long-Acting Incretin-Specific Behavioral Intervention.Obesity science & practice · 2026Article
- Joint Effect of Workplace Gender Discrimination and Gender Composition on the Mental Well-Being in Korean Workers.Safety and health at work · 2026Article
- Patient- and provider-level determinants of self-assessed health and well-being among adults with chronic conditions in Slovenian primary care.Health and quality of life outcomes · 2026Article
- Strengthening adolescent well-being-controlled feasibility from two Swedish upper secondary schools.BMC public health · 2026Article
- How Eudaimonia Impacts Global and Differential Life Satisfaction Independent of the General Mental Health Status.International journal of environmental research and public health · 2026Article
- Psychological Well-Being of Patients with Moderate-to-Severe Plaque Psoriasis Treated with Tildrakizumab: 28-Week Interim Results from a Multicenter Observational Study in Italy Using the DASS-21 Questionnaire, the BLUE Study.Dermatology and therapy · 2026Article
- Psychological Well-Being and Treatment Adherence in COPD Patients: A Correspondence Analysis of WHO-5, MARS, and GOLD Severity.Healthcare (Basel, Switzerland) · 2026Article
- Patient-Reported Well-Being in Value-Based Routine Care in Psoriatic Disease Using Tildrakizumab: 2-Year Data of the Phase IV POSITIVE Study.Psoriasis (Auckland, N.Z.) · 2026Article
- Sedentary accumulation patterns and mental health among university teachers: longitudinal evidence from a single-university two-wave cohort.Frontiers in psychology · 2026Article
- Psychometric validation and optimal cut-point determination of the Hausa WHO-5 well-being index for depression screening among internally displaced persons.Global mental health (Cambridge, England) · 2026Article
- Association of Internet Use Frequency and Purpose with Subjective Well-Being in Japanese Older Adults: A Cross-Sectional Exploratory Study from the Chofu-Digital-Choju Project.European journal of investigation in health, psychology and education · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince its first publication in 1998, the 5-item World Health Organization Well-being index, WHO-5, has become one of the most widely used questionnaires to assess subjective psychological well-being.
aimsTo perform a systematic review of the WHO-5 questionnaire, with a focus on its use across various disease areas and patient populations.
methodsStudies reporting the use of the WHO-5 were searched on the PubMed and PsycINFO databases (search December 2024). The classification of the different diseases or disorders was used following the 11th version of the International Classification of Diseases.
resultsA total of 552 studies met the predefined criteria for inclusion in the review. We provide an overview of the WHO-5 use in all different disease areas, the psychological burden of the patients, and if available, the impact of the treatments on their well-being. The groups with the most publications refer to the Coronavirus disease (COVID)-19 pandemic (n = 161, 29.2%) followed by the group of mental, behavioral, or neurodevelopmental disorders (n = 141, 25.6%), and the group of endocrine, nutritional, and metabolic diseases (n = 120, 21.7%).
conclusionsThe WHO-5 is a short questionnaire consisting of 5 positively formulated questions, which successfully detect when a disease impacts a person's subjective well-being. The scale proved to detect changes in well-being across various diseases around the world, and it should be considered in clinical practice and research.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.