Evidence map›Paper›PMID 40506603›Full record

ArticleNeurosurgical review2025

Analysis of carotid atherosclerotic plaque characteristics using optical coherence tomography.

Hao Feng, Xiaobing Li, Zequan Yu, Wei Liu

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Article in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hao FengDepartment of Neurology, Beijing Haidian Hospital, No.29 Zhongguancun Street, Haidian District, Beijing, 100080, China.
Xiaobing LiDepartment of Neurology, Beijing Haidian Hospital, No.29 Zhongguancun Street, Haidian District, Beijing, 100080, China.
Zequan YuDepartment of Neurology, Beijing Haidian Hospital, No.29 Zhongguancun Street, Haidian District, Beijing, 100080, China.
Wei LiuDepartment of Neurology, Beijing Haidian Hospital, No.29 Zhongguancun Street, Haidian District, Beijing, 100080, China. LiuWei0189@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study focused on the characteristics of carotid atherosclerotic plaques using Optical Coherence Tomography (OCT) and compared the plaque features between elderly and young-to-middle-aged patients.

methodsSeventy patients with carotid atherosclerotic stenosis underwent carotid OCT examination and were included in the study. Their demographic and clinical data, such as age, gender, coexisting conditions (including hypertension, hyperlipidemia, stroke, and coronary heart disease), smoking and medication histories, and biochemical parameters (fasting blood glucose, triglycerides, total cholesterol, high-density lipoprotein, and low-density lipoprotein) were documented. Additionally, characteristics of the carotid plaques (such as plaque rupture, minimum lumen area, fiber cap thickness, thrombus proportion, fibrous plaque, macrophage infiltration, and calcified plaque) were recorded. Based on age, patients were categorized into an elderly group (> 60 years) and a young-to-middle-aged group (≤ 60 years). Furthermore, they were stratified into symptomatic and asymptomatic groups according to the manifestation of symptoms. Comparisons of the aforementioned indicators were conducted across these groups.

resultsThe elderly group had a higher proportion of plaque rupture than the young-to-middle-aged group (P < 0.05). Additionally, the symptomatic group showed a lower detection rate of fibrous plaque compared to the asymptomatic group (P < 0.05). Conversely, the detection rates of plaque rupture and macrophage infiltration were significantly higher in the symptomatic group (P < 0.05).

conclusionOCT has evaluative value for the characteristics of carotid atherosclerotic stenosis plaques.

Indexed as

Carotid StenosisPlaque, AtheroscleroticTomography, Optical CoherenceAdultAgedFemaleHumansMaleMiddle AgedAtherosclerosisCarotid arteryEvaluative valueOptical coherence tomographyPlaquePlaque rupture

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.