Evidence map›Paper›PMID 40506599›Full record

ArticleBiological trace element research2026

Nano-Selenium supplementation Improves Meat Quality, Protein Deposition, and Selenoprotein Gene Expression in Channel Catfish (Ictalurus Punctatus).

Zi Meng Li, Xiao Min Jin, Hui Long Qiu, Wen Hao Xu, Cong Hu, Ke Chen, Jia Qiang Huang, Lian Shun Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zi Meng LiCollege of Fisheries an Life, Dalian Ocean University, Dalian, 116023, Liaoning, China.
Xiao Min JinHebei Key Laboratory of Ocean Dynamics Resources and Environments, Hebei Normal University of Science & Technology, Qinhuangdao, 066600, China.
Hui Long QiuHebei Key Laboratory of Ocean Dynamics Resources and Environments, Hebei Normal University of Science & Technology, Qinhuangdao, 066600, China.
Wen Hao XuHebei Key Laboratory of Ocean Dynamics Resources and Environments, Hebei Normal University of Science & Technology, Qinhuangdao, 066600, China.
Cong HuBeijing Dabeinong Technology Group Co.,Ltd, Beijing, 100080, China.
Ke ChenDepartment of Nutrition and Health, China Agricultural University, Beijing, 100083, China.
Jia Qiang HuangHebei Key Laboratory of Ocean Dynamics Resources and Environments, Hebei Normal University of Science & Technology, Qinhuangdao, 066600, China. jqhuang@cau.edu.cn.
Lian Shun WangCollege of Fisheries an Life, Dalian Ocean University, Dalian, 116023, Liaoning, China. wanglianshun@dlou.edu.cn.

Funding

the Science and Technology Special Project of Zaozhuang National Sustainable Development Agenda Innovation Demonstration Zone, China 2024SFOZX014
6 · The paper itself

Abstract

Selenium (Se) is a vital trace element for aquatic organisms. This study investigated the impact of dietary nano-selenium (Nano-Se) on growth, muscle nutritional quality, protein deposition, and selenoprotein gene expression in channel catfish (Ictalurus punctatus). A total of 12,000 catfish (85.74 ± 5.75 g) were randomly allocated into four groups (0, 1.5, 3.5, and 5.0 mg/kg Nano-Se) for 60 days. Optimal Nano-Se supplementation (3.5 mg/kg) significantly improved weight gain rate (WGR), specific growth rate (SGR), and feed conversion ratio (FCR) compared to the control. Additionally, Nano-Se enhanced muscle protein, lipid content, and free amino acid levels while modulating fatty acid composition, indicating improved flesh quality. Histological analysis revealed increased myofiber diameter, suggesting muscle growth promotion. Mechanistically, Nano-Se enhanced protein deposition by activating the PI3K/AKT/TOR pathway, stimulating protein synthesis, while simultaneously inhibiting proteolytic pathways (ubiquitin-proteasome and autophagy-lysosome systems). Furthermore, Nano-Se upregulated 17 key selenoprotein genes (Gpx1a, Gpx2, Gpx3, Gpx9, Selenoh, Selenoi, Selenok, Selenom, Selenop, Selenot1a, Selenot2, Selenow1, Selenow2, Selenoe, Selenoo1, Dio2, and Dio3b), implicating their roles in muscle development and oxidative stress regulation. The above results indicate that adding Nano-Se to feed can improve growth performance, flesh nutritional quality, muscle protein deposition, and selenoprotein genes expression of channel catfish.

Indexed as

Dietary SupplementsFish ProteinsIctaluridaeMeatSeleniumSelenoproteinsAnimalsMuscle ProteinsFish ProteinsMuscle ProteinsSeleniumSelenoproteinsIctalurus punctatusMuscle protein depositionNutritional qualitySeleniumSelenoproteins

Identifiers

PMID40506599

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.